H-L-Photo-lysine-hydrochloride-DataSheet-生命科学试剂-MedChemExpress

Hotline:400-820-3792Inhibitors•Agonists•ScreeningLibrarieswww.MedChemEH-L-Photo-lysinehydrochlorideCat.No.:HY-D0853A分⼦式:C₁₁H₂₁ClN₄O₄分⼦量:308.76作⽤靶点:Others作⽤通路:Others储存⽅式:4°C,sealedstorage,awayfrommoisture*Insolvent:-80°C,6months;-20°C,1month(sealed

storage,awayfrommoisture)溶解性数据体外实验DMSO:250mg/mL(809.69mM;Needultrasonic)MassSolvent1mg5mg10mgConcentration制备储备液1mM3.2388mL16.1938mL32.3876mL5mM0.6478mL3.2388mL6.4775mL10mM0.3239mL1.6194mL3.2388mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存⽅式和期限。体内实验请根据您的实验动物和给药⽅式选择适当的溶解⽅案，配制前请先配制澄的储备液，再依次添加助溶剂(为保证实验结果的可靠性，体内实验的⼯作液，建议您现⽤现配，当天使⽤；澄的储备液可以根据储存条件，适当保存；以下溶剂前的百分⽐指该溶剂在您配制终溶液中的体积占⽐)：1.请依序添加每种溶剂：10%DMSO>>40%PEG300>>5%Tween-80>>45%salineSolubility:≥2.08mg/mL(6.74mM);Clearsolution2.请依序添加每种溶剂：10%DMSO>>90%(20%SBE-β-CDinsaline)Solubility:≥2.08mg/mL(6.74mM);ClearsolutionBIOLOGICALACTIVITY⽣物活性H-L-Photo-lysinehydrochloride⼀种含有重氮的赖氨酸氨酸，也⼀种光交联剂。H-L-Photo-lysine1/2MasterofSmallMolecules—您⾝边的抑制剂⼤师www.MedChemEhydrochloride可以选择性的插⼊到蛋⽩质中，并⽤于在体外和活细胞中交联蛋⽩质-蛋⽩质相互作⽤。H-L-Photo-lysinehydrochloride⽤作紫外光激活的光交联探针。体外研究Photo-lysine,whichisreadilyincorporatedintoproteinsbynativemammaliantranslationmachinery,canbeusedtocaptureandidentifyproteinsthatrecognizelysinepost-translationalmodifications(PTMs),including'readers'and'erasers'ofhistonemodifications[2].•NatBiotechnol.2020Oct19.Seemorecustomervalidationsonwww.MedChemEREFERENCES[1].AiHW,etal.Probingprotein-proteininteractionswithageneticallyencodedphoto-crosslinkingaminoacid.Chembiochem.2011Aug16;12(12):1854-7.[2].ChatterjeeA,etal.Efficientviraldeliverysystemforunnaturalaminoacidmutagenesisinmammaliancells.ProcNatlAcadSciUSA.2013Jul16;110(29):11803-8.[3].YangT,etal.Photo-lysinecapturesproteinsthatbindlysinepost-translationalmodifications.NatChemBiol.2016Feb;12(2):70-2.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel