Antibacterial-agent-117-DataSheet-生命科学试剂-MedChemExpress

Hotline:400-820-3792Inhibitors•ScreeningLibraries•Proteinswww.MedChemEAntibacterialagent117Cat.No.:HY-W282615CASNo.:341944-06-7分⼦式:C₉H₉ClN₄S分⼦量:240.71作⽤靶点:Bacterial作⽤通路:Anti-infection储存⽅式:4°C,protectfromlight*Insolvent:-80°C,6months;-20°C,1month(protectfrom

light)溶解性数据体外实验DMSO:100mg/mL(415.44mM;Needultrasonic)MassSolvent1mg5mg10mgConcentration制备储备液1mM4.1544mL20.7719mL41.5438mL5mM0.8309mL4.1544mL8.3088mL10mM0.4154mL2.0772mL4.1544mL请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；⼀旦配成溶液，请分装保存，避免反复冻融造成的产品失效。储备液的保存⽅式和期限：-80°C,6months;-20°C,1month(protectfromlight)。-80°C储存时，请在6个⽉内使⽤，-20°C储存时，请在1个⽉内使⽤。BIOLOGICALACTIVITY⽣物活性Antibacterialagent117，三唑衍⽣物，⼀种抗剂。Antibacterialagent117对R.prowazekiiMetAP1(RpMetAP1)有抑制作⽤，其IC50值为15μM。Antibacterialagent117也可抑制⽴克次体⽣长，可⽤于感染的研究。IC50&TargetIC50:15μM(RpMetAP1)[1]1/2MasterofBioactiveMolecules—您⾝边的抑制剂⼤师www.MedChemE体外研究Antibacterialagent117caninhibitRpMetAP1withanIC50valueof15μM[1].Antibacterialagent117(0.3μM,3μM,30μMand300μM)stimulatesendothelialcell(EC)metabolismandalsoinhibitsrickettsialgrowth[1].REFERENCES[1].TravisRHelgren,etal.Rickettsiaprowazekiimethionineaminopeptidaseasapromisingtargetforthedevelopmentofantibacterialagents.BioorgMedChemMcePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792ax:02