制药工程专业英语Unit11

capsulesemulsionsyruptabletsuspensionointmentcreamelixir胶囊乳剂糖浆片剂混悬剂软膏霜剂酒剂第1页/共9页第一页，共10页。Theparenteralrouteofadministrationisimportantintreatingmedicalemergencies（inwhichasubjectiscomatoseorcannotswallow）,andinprovidingvarioustypesofmaintenancetherapyforhospitalizedpatients.第2页/共9页第二页，共10页。Ifpatientself-administrationcannotbeachieved,thesalesofthedrugconstituteonlyasmallfractionofwhatthemarketwouldbeotherwise.第3页/共9页第三页，共10页。

Thereasonsforthispreferenceareasfollows.Tabletsandcapsulesrepresentunitdosageformsinwhichoneusualdoseofthedrughasbeenaccuratelyplaced.Bycomparison,liquidoraldosageforms,suchassyrups,suspensions,emulsions,solutions,andelixirs,areusuallydesignedtocontainonedoseofmedicationin5to30ml.

第4页/共9页第四页，共10页。PropertiesTheobjectiveofthedesignandmanufactureofthecompressedtabletistodeliverorallythecorrectamountofdrugintheproperformatoroverthepropertimeandinthedesiredlocation,andtohaveitschemicalintegrityprotectedtothatpoint.Asidefromthephysicalandchemicalpropertiesofthemedicinalagent(s)tobeformulatedintoatablet,theactualphysicaldesign,manufacturingprocess,andcompletechemicalmakeupofthetabletcanhaveaprofoundeffectontheefficacyofthedrug(s)beingadministered.第5页/共9页第五页，共10页。Atablet(1)shouldbeanelegantproducthavingitsownidentitywhilebeingfreeofdefectssuchaschips,cracks,discoloration,contamination,andthelike;(2)shouldhavethestrengthtowithstandtherigorsofmechanicalshocksencounteredinitsproduction,packaging,shipping,anddispensing;and(3)shouldhavethechemicalandphysicalstabilitytomaintainitsphysicalattributeovertime.第6页/共9页第六页，共10页。Pharmaceuticalscientistsnowunderstandthatvariousphysicalpropertiesoftabletscanundergochangeunderenvironmentalorstressconditions,andthatphysicalstability,throughitseffectonbioavailabilityinparticular,canbeofmoresignificanceandconcerninsometabletsystemsthanchemicalstability.第7页/共9页第七页，共10页。8Thankyou第8页/共9页第八页，共10页。9谢谢您的观看！第9页/共9页第九页，共10页。内容总结capsules。and(3