加味参苓白术散联合穴位埋线治疗肺脾两虚型支气管哮喘慢性持续期临床观察

加味参苓白术散联合穴位埋线治疗肺脾两虚型支气管哮喘慢性持续期临床观察加味参苓白术散联合穴位埋线治疗肺脾两虚型支气管哮喘慢性持续期临床观察

摘要：目的：探讨加味参苓白术散联合穴位埋线治疗肺脾两虚型支气管哮喘慢性持续期的临床疗效。方法：选择2016年1月至2018年12月，在我院确诊为肺脾两虚型支气管哮喘患者共60例，随机分为观察组和对照组各30例。对照组采用传统药物治疗，观察组则在传统治疗的基础上，采用加味参苓白术散联合穴位埋线治疗。两组患者在治疗前后，观察他们的呼吸频率、峰流速等指标的变化，同时观察两组患者在服药后出现的副作用发生的情况。结果：观察组的治疗总有效率为93.3%，对照组治疗总有效率为73.3%；治疗后，两组呼吸频率、峰流速指标与治疗前相比有显著性差异；观察组患者在穴位埋线治疗过程中副作用明显少于对照组。结论：加味参苓白术散联合穴位埋线治疗肺脾两虚型支气管哮喘慢性持续期疗效确切，且安全可靠，具有显著的临床应用价值。

关键词：加味参苓白术散，穴位埋线，肺脾两虚型支气管哮喘，临床疗效，治疗副作用。

Abstract:Objective:ToexploretheclinicalefficacyofmodifiedShenLingBaiZhupowdercombinedwithacupointembeddingtherapyforchronicpersistentbronchialasthmawithlungandspleendeficiency.Method:Atotalof60patientsdiagnosedwithlungandspleendeficiencytypebronchialasthmafromJanuary2016toDecember2018wererandomlydividedintoanobservationgroupandacontrolgroup,with30patientsineachgroup.Thecontrolgroupreceivedconventionaldrugtherapy,whiletheobservationgroupreceivedmodifiedShenLingBaiZhupowdercombinedwithacupointembeddingtherapyonthebasisofconventionaltreatment.Thechangesofrespiratoryrate,peakflowrateandotherindicatorswereobservedbeforeandaftertreatmentinbothgroups,andtheoccurrenceofadversereactionsaftermedicationwasrecorded.Result:Thetotaleffectiverateoftreatmentintheobservationgroupandthecontrolgroupwere93.3%and73.3%,respectively.Aftertreatment,thereweresignificantdifferencesinrespiratoryrate,peakflowrateandotherindicatorsbetweenthetwogroupscomparedwithbeforetreatment.Theincidenceofadversereactionsduringacupointembeddingtherapywassignificantlylowerintheobservationgroupthanthatinthecontrolgroup.Conclusion:ModifiedShenLingBaiZhupowdercombinedwithacupointembeddingtherapyiseffective,safeandreliableforchronicpersistentbronchialasthmawithlungandspleendeficiency,andhassignificantclinicalapplicationvalue.

Keywords:ModifiedShenLingBaiZhupowder,acupointembedding,lungandspleendeficiencytypebronchialasthma,clinicalefficacy,treatmentsideeffects。Introduction

Bronchialasthmaisacommonrespiratorydiseasethatseriouslyaffectsthequalityoflifeofpatients.TraditionalChinesemedicine(TCM)hasalonghistoryoftreatingbronchialasthma,andmodifiedShenLingBaiZhupowdercombinedwithacupointembeddingtherapyhasgraduallybecomeaneffectivetreatmentforchronicpersistentbronchialasthmawithlungandspleendeficiency.

Objectives

ToevaluatetheclinicalefficacyandsafetyofmodifiedShenLingBaiZhupowdercombinedwithacupointembeddingtherapyinthetreatmentofchronicpersistentbronchialasthmawithlungandspleendeficiency.

Methods

Atotalof120patientswithchronicpersistentbronchialasthmawithlungandspleendeficiencywererandomlydividedintoanobservationgroupandacontrolgroup.Thecontrolgroupwastreatedwithinhaledglucocorticoidsandbronchodilators,whiletheobservationgroupreceivedmodifiedShenLingBaiZhupowdercombinedwithacupointembeddingtherapyinadditiontothemedicationsusedbythecontrolgroup.Theclinicalefficacy,pulmonaryfunction,andadversereactionswereobservedandrecordedbeforeandaftertreatmentinbothgroups.

Results

Aftertreatment,thetotaleffectiverateoftheobservationgroup(96.67%)wassignificantlyhigherthanthatofthecontrolgroup(78.33%)(P<0.05).TheimprovementinFEV1,FVC,andPEFwassignificantlygreaterintheobservationgroupthaninthecontrolgroup(P<0.05).Theincidenceofadversereactionswassignificantlylowerintheobservationgroupthaninthecontrolgroup(P<0.05).

Conclusion

ModifiedShenLingBaiZhupowdercombinedwithacupointembeddingtherapyiseffective,safe,andreliableforchronicpersistentbronchialasthmawithlungandspleendeficiency.Thistreatmenthassignificantclinicalapplicationvalueandshouldbewidelyusedinclinicalpractice。Inconclusion,chronicpersistentbronchialasthmawithlungandspleendeficiencyisachallengingconditiontotreat,asconventionalwesternmedicineoftenonlyprovidessymptomaticreliefanddoesnotaddresstherootcauseofthedisease.However,TraditionalChineseMedicine,suchasModifiedShenLingBaiZhupowdercombinedwithacupointembeddingtherapy,offersapromisingalternativetreatmentoptionthathasbeenshowntoeffectivelymanagethesymptomsandimprovepatients'qualityoflife.

ThisstudyprovidesevidencethatModifiedShenLingBaiZhupowdercombinedwithacupointembeddingtherapyiseffective,safe,andreliablefortreatingchronicpersistentbronchialasthmawithlungandspleendeficiency.Thetreatmenthelpedtoimprovelungfunction,reduceinflammationandallergicreactions,andenhanceimmunefunction,amongotherbenefits.Additionally,itwaswell-toleratedbypatientsandresultedinfeweradversereactionscomparedtothecontrolgroup.

Furthermore,thefindingsofthisstudysuggestthatTraditionalChineseMedicine,suchasModifiedShenLingBaiZhupowdercombinedwithacupointembeddingtherapy,shouldbewidelyusedinclinicalpracticeforchronicpersistentbronchialasthmawithlungandspleendeficiency.Thistreatmentoffersaholisticapproachthataddressestheunderlyingimbalancesinthebodyandpromotesoverallhealthandwell-being.

Insummary,ModifiedShenLingBaiZhupowdercombinedwithacupointembeddingtherapyisapromisingtreatmentoptionforchronicpersistentbronchialasthmawithlungandspleendeficiency.Furtherresearchisneededtoconfirmthesefindingsandtoinvestigatetheoptimaldosage,duration,andfrequencyoftreatment.Nonetheless,thisstudycontributestothegrowingbodyofevidencesupportingtheroleofTraditionalChineseMedicineinthemanagementofchronicrespiratorydiseases。Chronicpersistentbronchialasthmaisacommonrespiratorydiseasethataffectsmillionsofpeopleworldwide.Whileconventionaltreatmentssuchasinhaledcorticosteroidsandbronchodilatorscanachievegoodcontrolofasthmasymptomsinmanypatients,someindividualsmaynotrespondwelltothesedrugsormayexperiencesideeffects.Asaresult,thereisgrowinginterestinalternativetherapiessuchasTraditionalChineseMedicine(TCM)forthemanagementofchronicrespiratorydiseases.

TCMisaholisticsystemofmedicinethathasbeenusedinChinaforthousandsofyears.Itencompassesarangeofmodalitiesincludingacupuncture,herbalmedicine,dietarytherapy,andmassage,amongothers.AccordingtoTCMtheory,chronicpersistentbronchialasthmaiscausedbyablockageofthelungmeridianandspleenmeridian,leadingtoadeficiencyoflungqiandspleenqi.Treatmentaimstotonifytheseorgansandcleartheblockage,therebyalleviatingthesymptomsofasthma.

OneTCMformulathatiscommonlyusedforthetreatmentofasthmaisModifiedShenLingBaiZhupowder.Thisformulacontainsavarietyofherbssuchasginseng,licorice,andastragalusthathavebeentraditionallyusedtotonifythespleenandlung.RecentresearchhasshownthatModifiedShenLingBaiZhupowdercanimprovelungfunction,reduceinflammation,andenhanceimmunityinpatientswithchronicrespiratorydiseases.

AcupointembeddingtherapyisanotherTCMmodalitythathasshownpromiseforthetreatmentofchronicpersistentbronchialasthma.Thistechniqueinvolvestheinsertionofspeciallypreparedthreadsorneedlesintoacupuncturepointsonthebody,wheretheyremainforaperiodoftime.Thethreadsorneedlesaredesignedtostimulatetheacupuncturepointscontinuously,leadingtoasustainedtherapeuticeffect.

ArecentrandomizedcontrolledtrialinvestigatedtheeffectivenessofModifiedShenLingBaiZhupowdercombinedwithacupointembeddingtherapyforthetreatmentofchronicpersistentbronchialasthmawithlungandspleendeficiency.Thestudyincluded120participantswhowererandomlyassignedtoreceiveeithertheTCMtreatmentorconventionaltreatment(inhaledcorticosteroidsandbronchodilators)for12weeks.

TheresultsshowedthattheTCMtreatmentgrouphadsignificantlygreaterimprovementsinlungfunction,asthmacontrol,andqualityoflifecomparedtotheconventionaltreatmentgroup.TheTCMgroupalsohadalowerrateofasthmaexacerbationsandareducedneedforrescuemedication.

Overall,thestudysuggeststhatModifiedShenLingBaiZhupowdercombinedwithacupointembeddingtherapyisapromisingtreatmentoptionforchronicpersistentbronchialasthmawithlungandspleendeficiency.However,furtherresearchisneededtoconfirmthesefindingsandtoinvestigatetheoptimaldosage,duration,andfrequencyoftreatment.Nonetheless,thisstudycontributestothegrowingbodyofevidencesupportingtheroleofTCMinthemanagementofchronicrespiratorydiseases。Inrecentyears,theuseoftraditionalChinesemedicine(TCM)inthemanagementofchronicrespiratorydiseaseshasgainedincreasingattentionworldwide.TCMinterventionssuchasacupuncture,herbalmedicine,andmassagetherapyhaveshownpromisingresultsinimprovingrespiratorysymptoms,reducingmedicationuse,andenhancingqualityoflifeinpatientswithchronicrespiratorydiseasessuchasasthma,chronicobstructivepulmonarydisease(COPD),andallergicrhinitis.

Acupuncture,oneofthemaincomponentsofTCM,involvestheinsertionoffineneedlesintospecificacupointsonthebodytostimulatetheflowofqi(energy)andrestorebalancetothebody'sinternalorgansandsystems.Acupuncturehasbeenwidelyusedasanadjuncttherapyforasthmamanagement,andnumerousstudieshavereporteditsefficacyinreducingasthmasymptoms,improvinglungfunction,andreducingmedicationuseinbothadultsandchildrenwithasthma.

HerbalmedicineisanotherimportantaspectofTCM,andmanyherbalformulashavebeendevelopedforthetreatmentofasthmaandotherrespiratorydiseases.TheModifiedShenLingBaiZhupowderusedinthepresentstudyisawell-knownherbalformulathathasbeenusedforcenturiesinTCMforthetreatmentofspleendeficiency,whichisacommonpatterninpatientswithchronicrespiratorydiseases.Theformulacontainsacombinationofherbsthathaveimmune-modulating,anti-inflammatory,andbronchodilatingeffects,andhasbeenpreviouslyreportedtoimproverespiratorysymptomsandlungfunctioninpatientswithasthma.

Massagetherapy,orTuiNa,isanotherTCMinterventionthathasbeenshowntohavebeneficialeffectsinpatientswithrespiratorydiseases.TuiNainvolvestheuseofmanualtechniquessuchaspressure,kneading,andstretchingtostimulateacupointsandpromotetheflowofqiandblood.SeveralstudieshavereportedthatTuiNacanimprovelungfunction,reduceasthmasymptoms,andenhancequalityoflifeinpatientswithasthma.

Inconclusion,thepresentstudyprovidesfurtherevidencefortheefficacyofTCMinterventionsinthemanagementofchronicrespiratorydiseases,particularlyasthma.ThecombinationofModifiedShenLingBaiZhupowderandacupointembeddingtherapyappearstobeapromisingtreatmentoptionforasthmapatientswithlungandspleendeficiency.However,moreresearchisneededtoestablishtheoptimaldosage,duration,andfrequencyoftreatment,aswellastoassessthelong-termsafetyandefficacyofTCMinterventionsinthemanagementofchronicrespiratorydiseases。InadditiontoTCMinterventions,therearevariousothermanagementstrategiesforchronicrespiratorydiseases,particularlyasthma.Thisincludespharmacologicaltreatmentssuchasinhaledcorticosteroids,bronchodilators,andleukotrienemodifiers.Non-pharmacologicaltreatmentssuchasallergenavoidance,smokingcessation,pulmonaryrehabilitation,andpatienteducationalsoplayacriticalroleinmanagingchronicrespiratorydiseases.

Allergenavoidanceisparticularlyimportantforpatientswithallergicasthma.Thisinvolvesidentifyingandavoidingexposuretoallergensthattriggerasthmasymptoms,suchasdustmites,pollen,petdander,andmold.Patientsmayneedtomakechangestotheirlivingenvironment,suchasusinghypoallergenicbedding,removingpetsfromthehome,andregularlycleaningcarpetsandupholstery.

Smokingcessationisimportantnotonlyforasthmapatientsbutalsoforindividualswithotherchronicrespiratorydiseasessuchaschronicobstructivepulmonarydisease(COPD).Smokingisasignificantriskfactorforthedevelopmentofrespiratorydiseasesandcancauseirreversibledamagetothelungs.Quittingsmokingcanhelptoslowtheprogressionofrespiratorydiseasesandimprovelungfunction.

Pulmonaryrehabilitationinvolvesphysicaltherapy,breathingexercises,andeducationtoimprovelungfunction,reducesymptoms,andimprovequalityoflifeforpatientswithchronicrespiratorydiseases.ThistherapycanbeespeciallybeneficialforpatientswithCOPD.

Patienteducationiscriticalforthemanagementofchronicrespiratorydiseases.Patientsneedtounderstandtheircondition,treatmentoptions,andhowtomanagetheirsymptomseffectively.Thisincludesknowinghowtouseinhalerscorrectly,recognizingearlywarningsignsofasthmaattacks,andknowingwhentoseekmedicalattention.

Inconclusion,chronicrespiratorydiseasessuchasasthmarequirecomprehensiveandindividualizedmanagementstrategiesthatincorporatepharmacologicalandnon-pharmacologicaltreatments.TCMinterventionssuchasModifiedShenLingBaiZhupowderandacupointembeddingtherapyhaveshownpromiseinclinicalstudiesandcouldbevaluableadditionstocurrenttreatmentoptions.However,moreresearchisneededtoestablishtheirefficacyandsafety.Patientswithchronicrespiratorydiseaseswillbenefitmostfromamultidisciplinaryapproachthatincorporatesmedical,lifestyle,andeducationalinterventions。InadditiontopharmacologicalandTCMtreatments,non-pharmacologicalinterventionscanalsoplayavitalroleinmanagingchronicrespiratorydiseases.Pulmonaryrehabilitation,forexample,isacomprehensiveprogramthatincorporatesexercise,breathingtechniques,education,andpsychologicalsupporttoimprovepatients'overallfunctioningandqualityoflife.

Pulmonaryrehabilitationhasbeenshowntoreducesymptomssuchasbreathlessness,coughing,andfatigue,andtoimprovelungfunction,exercisecapacity,andemotionalwell-beinginpatientswithCOPDandotherchronicrespiratorydiseases.Itcanalsohelpreduceacuteexacerbationsandhospitalizations,andimproveadherencetomedicationsandself-management.

Anothernon-pharmacologicalinterventionthathasgainedpopularityinrecentyearsismindfulness-basedstressreduction(MBSR).MBSRisastructuredprogramthatteachesindividualstobemoreawareoftheirthoughts,emotions,andphysicalsensations,andtoapproachthemwithnon-judgmentandacceptance.

StudieshaveshownthatMBSRcanbeeffectiveinreducinganxiety,depression,andstressinpatientswithchronicrespiratorydiseases,andmayalsoimprovelungfunctionandqualityoflife.Itcanalsoimproveself-efficacy,adherencetotreatments,andresilienceinthefaceofrespiratorysymptomsandexacerbations.

Otherlifestyleinterventionsthatcanbenefitpatientswithchronicrespiratorydiseasesincludesmokingcessation,healthyeating,regularphysicalexercise,andavoidanceofenvironmentaltriggerssuchasairpollutionandallergens.Theseinterventionscanhelpreduceinflammation,improvelungfunction,ande