Ferulic-acid-4-O-sulfate-Ferulic-acid-4-sulfate-DataSheet-生命科学试剂-MCE

Hotline:400-820-3792Inhibitors•ScreeningLibraries•Proteinswww.MedChemEFerulicacid4-O-sulfateCat.No.:HY-147323CASNo.:86321-29-1Synonyms:Ferulicacid4-sulfate分⼦式:C₁₀H₁₀O₇S分⼦量:274.25作⽤靶点:DrugMetabolite作⽤通路:MetabolicEnzyme/Protease储存⽅式:Powder-20°C3yearsInsolvent-80°C6months-20°C1month溶解性数据体外实验DMSO:10mg/mL(36.46mM;ultrasonicandwarmingandheatto60°C)MassSolvent1mg5mg10mgConcentration制备储备液1mM3.6463mL18.2315mL36.4631mL5mM0.7293mL3.6463mL7.2926mL10mM0.3646mL1.8232mL3.6463mL请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；⼀旦配成溶液，请分装保存，避免反复冻融造成的产品失效。储备液的保存⽅式和期限：-80°C,6months;-20°C,1month。-80°C储存时，请在6个⽉内使⽤，-20°C储存时，请在1个⽉内使⽤。BIOLOGICALACTIVITY⽣物活性Ferulicacid4-O-sulfate(Ferulicacid4-sulfate)Ferulicacid(HY-N0060)的代谢物。Ferulicacid4-O-sulfate可以放松⼩⿏的动脉，降低⾎压。体外研究Ferulicacid4-O-sulfate(0.1-30μM)causessignificantconcentration-dependentrelaxationsinmouseaorta,femoralandsaphenousarteries[1].1/2MasterofBioactiveMolecules—您⾝边的抑制剂⼤师www.MedChemE体内研究Ferulicacid4-O-sulfate(16.13and161.3µg/kg;i.v.;once)relaxesarteriesandlowersbloodpressureinmice[1].AnimalModel:MaleSwissmice[1]Dosage:16.13and161.3µg/kgAdministration:Intravenousinjection,onceResult:Significantlydecreasedthemeanarterialpressure(MAP)immediatelyafterintravenousinjection.REFERENCES[1].VanRymenantE,etal.Ferulicacid-4-O-sulfateratherthanferulicacidrelaxesarteriesandlowersbloodpressureinmice.JNutrBiochem.2017Jun;44:44-51.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792;021-589559