天然药化课件 (英文)

NaturalProductsChemistry唐万侠(TangWanxia)2012-2013(2)BilingualTeachingMethodsExplaintheknowledgeinEnglishandChinese.Payattentiontothecultureexchangeintheworld.ImprovetheabilitytoutilizespecialtyEnglish.ExaminationforNaturalProductsChemistrySelectiveCourse1.Cometotheclassontime:10

2.Behaviourinclass:

10

3.Classnote:

10

4.Examinationattheendoftheclass:70Note:Someonecan’tbeallowedtocometotheexaminationifheisabsentfromtheclassmorethan6times.ClassContentsChapter1IntroductionChapter2SaccharideandGlycosidesChapter3PhenylpropanoidsChapter4QuinonesChapter5FlavonoidsChapter6TerpenoidsandVolatileoilsChapter7TriterpenoidsandSaponinsChapter8SteroidesandGlycosidesChapter9AlkaloidsChapter10MarineNaturalProducts糖和苷苯丙素类化合物醌类化合物黄酮类化合物萜类和挥发油三萜及其苷类甾体及其苷类生物碱海洋天然药物

1、Outline3、Extractandisolationmethods4、Structuralelucidationmethods2、BiosynthesisChapter1Introduction1、OutlineDefinition:Naturalproductschemistryisasubjecttoresearchthechemicalconstituentsofnaturalmedicinalplantsonthebaseofmodernscientifictheoryandmethods.

Contents：Structuralcharacteristics,physicochemicalproperties,extractandisolationmethods,andstructuralelucidationofthechemicalconstituentsofallkindsofnaturalmedicinalplants.

Researchresource:Naturalplants(major),animals,minerals,andmicroorganism.1、OutlineNaturalmedicinalplantsherbmedicine麻黄(Ephedraspp.)1、Outline1、Outline槐花米（Sophorajaponica）1、Outline

1、OutlineDevelopmentsinforeigncountries●

In1769,tartar(potassiumhydrogentartrate)

wastransferredtocalciumsaltanddecomposedinsulphuricacidtoproducetartaricacid.(K.W.Schelle,Swedish)●In1804,morphinewasisolatedfromopium(Dorosine,French)●In1806,

morphinewasisolatedfromopium(Serturner,German)●In1810-1860,

theperiodofalkaloiddevelopment1、OutlineSpectroscopicanalysis:

NMR,MS,IR,andUV.Researchmethods:

extractandisolationguidedbybioactivescanning,structuralmodification,andtotalsynthesis.1、OutlineDevelopmentofnowadays

1、Outline3、Extractandisolationmethods4、Structuralelucidationmethods2、BiosynthesisChapter1Introduction2、BiosynthesisCO2H2O葡萄糖代谢磷酸烯醇式丙酮酸丙酮酸乙酰辅酶A丙二酸