缺铁性贫血英文版

IrondeficiencyanemiaCONTENTSINTRODUCTIONETIOLOGY/PATHOGENESISMANIFESTATIONSLABORATORYFINDINGSDIAGNOSIS&DIFFERENTIALTREATMENTCASEREPORTIrondeficiencyanemia(IDA)Theanemiacausedbyinsufficientdietaryironuptake,bleeding,etal,inwhichtheironstorageandhemoglobinsynthesisdecreased.Irondeficiencyistheleadingcauseofanmeiaworldwide.hemoglobinhemeglobinFe++protoporphyrinSerumironCausesDecreaseofintakeBloodlossIncreaseofneedsDietarydeficiencygastrointestinalpregnancyGastricdiseaseulcerbabycancerhookworm

diseasehaemorrhoidsmenstruationhemolysisMANIFESTATIONSMANIFESTATIONSPrimarydiseaseanemiaMenifestationofanemia1,commonmenifestation:pale,weak,dizzy,tinnitus,palpitation2,specialmenifestation:Tests---morphology---bloodMCV<80flMCH<26pgMCHC<32%Tests---morphology---bonemarrowTests---ironmetabolismSerumironTotalironbindingcapacity,TIBCTransferrinsatuationSerumferritinFEP(freeerythrocyteprotoporphyrin)DIAGNOSISThreestages1,irondepletion:serumferritin,serumironnormal2,latentirondeficiencyserumiron,serumferritin,FEP,TIBC,HBnormal3,IDADIFFERENTIAL1,thalassemia2,anemiaofchronicdiseaseserumiron,serumferritin,TIBCnormal,ringedsideroblast3,ringedsiderblastanemiaringedsideroblast,>15%treatmentTreatmentofprimarydiseaseIronsupplementation(TargetHb-presentHb)*kg*0.33(TargetHb-presentHb)*kg*0.24+500TreatmentresponseRet:d7-10Hemoglobin:week2Hemogolbin:1-2monthlaternormalFerritin:continuesupplement3monthsCasereportA20-year-oldfemalepresentedwithfatigue,paleinAugust2014.ShewasadmittedtoThe1stAffiliated,GMU.Physicalexaminationfoundthatnosternumtendernessandnoenlargementofliverandspleen.TESTShepresentedwithandecreasedleukocytecountof2.5×109/L,anaemiawithhaemoglobinof54g/l，RBCcountof3.4×1012/L,MCV55.9fL，MCH:15.9pg，MCHC:284g/L.Plateletcountof343×109/L.Serumiron6.2umol/L，TIBC:89.1umol/LSerumferritin:18.94ng/mLCD55/59normal,thalassemiagenetestnormaldianosisIronDeficiencyAnemiaWhatwasthecauseofIDA?decreaseofintake:sheeatedlittlemeat.bloodloss:hermenstruationwasnormal.

gastroscopeshowederosionofstomach

treatmentChangethewayofdietTreattheerosionofstomachInfusionIronsupplementation