N-羟基邻苯二甲酰亚胺酯在光催化烷基化反应中的研究进展（英文）

N-羟基邻苯二甲酰亚胺酯在光催化烷基化反应中的研究进展（英文）Title:ResearchProgressonPhotocatalyticAlkylationReactionofN-HydroxyphthalimideEstersAbstract:N-Hydroxyphthalimideestershaveemergedasversatilereagentsinorganicsynthesisduetotheirabilitytoundergoselectivefunctionalizationreactionsundermildreactionconditions.Inrecentyears,theapplicationofphotocatalysisinalkylationsusingN-hydroxyphthalimideestersasalkylatingagentshasgainedsignificantattention.Thisreviewprovidesacomprehensiveoverviewoftherecentadvancementsinthefieldofphotoredox-mediatedalkylationreactionsusingN-hydroxyphthalimideesters.Thevariousmechanisms,reactionconditions,andsyntheticapplicationsofthismethodologyarediscussed.1.Introduction1.1Background1.2ImportanceofN-HydroxyphthalimideEstersinOrganicSynthesis1.3Light-inducedCatalysis2.PhotocatalyticAlkylationReactions2.1Mechanism2.2Photocatalysts2.2.1TransitionMetalComplexes2.2.2OrganicDyes2.2.3SemiconductorMaterials2.3ReactionConditions2.3.1LightSources2.3.2Solvents2.3.3Temperature2.4ReactionScopeandSyntheticApplications2.4.1AlkylationofC-HBonds2.4.2AlkylationofHeteroatoms2.4.3Alkylationofα,β-UnsaturatedCompounds2.4.4AlkylationofC-CMultipleBonds3.ChallengesandLimitations3.1RegioselectivityandSite-SelectiveAlkylations3.2SubstrateScope3.3CatalystStabilityandReactivity4.FuturePerspectivesandOutlook4.1DevelopmentofNewPhotocatalysts4.2ExpansionofAlkylationSubstrates4.3MechanisticInvestigations4.4ApplicationinTotalSynthesis5.ConclusionsReferencesIntroduction:TheintroductionsectionprovidesabriefbackgroundontheimportanceofN-hydroxyphthalimideestersinorganicsynthesisandtheadvantagesofusingphotocatalysisinalkylations.Ithighlightstherelevanceandsignificanceoftheresearchtopic.PhotocatalyticAlkylationReactions:Thissectionelaboratesonthemechanismofthephotoredox-mediatedalkylationreactionsusingN-hydroxyphthalimideestersasalkylatingagents.Itdiscussesvarioustypesofphotocatalysts,includingtransitionmetalcomplexes,organicdyes,andsemiconductormaterials.Thereactionconditionssuchaslightsources,solvents,andtemperaturearealsodescribed.Furthermore,thesyntheticapplicationsofthismethodology,includingthealkylationofC-Hbonds,heteroatoms,α,β-unsaturatedcompounds,andC-Cmultiplebonds,areoutlined.ChallengesandLimitations:Here,thechallengesandlimitationsassociatedwithphotocatalyticalkylationreactionsusingN-hydroxyphthalimideestersarediscussed.Theregioselectivityandsite-selectivityissues,substratescope,andcatalyststabilityandreactivityarehighlighted.FuturePerspectivesandOutlook:Thissectionprovidesanoutlookonthefuturedevelopmentofthefield.Itdiscussesthepotentialforthediscoveryofnewphotocatalysts,theexpansionofalkylationsubstrates,theneedformechanisticinvestigations,andtheapplicationofthismethodologyintotalsynthesis.Conclusions:TheconcludingsectionsummarizesthekeyfindingsoftheresearchandemphasizestheimportanceofphotocatalyticalkylationreactionsusingN-hydroxyphthalimideesters.Italsosuggestsfuturedirectionsforresearchandpotentialapplications.References:Alistofrelevantreferencescitedinthereviewisprovided.Note:Thecontentaboveisanoutlinefor