Hydroxyzine-dihydrochloride-Standard-DataSheet-生命科学试剂-MCE

Hotline:400-820-3792Inhibitors • ScreeningLibraries • Proteinswww.MedChemEHydroxyzinedihydrochloride(Standard)Cat.No.:HY-B0548ARCASNo.:2192-20-3分子式:C₂₁H₂₉Cl₃N₂O₂分子量:447.83作用靶点:HistamineReceptor作用通路:GPCR/GProtein;Immunology/Inflammation;NeuronalSignaling储存方式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.溶解性数据体外实验H2O:≥150mg/mL(334.95mM)*"≥"meanssoluble,butsaturationunknown.MassSolvent1mg5mg10mgConcentration制备储备液1mM2.2330mL11.1650mL22.3299mL5mM0.4466mL2.2330mL4.4660mL10mM0.2233mL1.1165mL2.2330mLBIOLOGICALACTIVITY生物活性Hydroxyzine(dihydrochloride)(Standard)是Hydroxyzine(dihydrochloride)的分析标准品。本产品用于研究及分析应用。Hydroxyzinedihydrochloride，一种苯二氮卓抗组胺剂(antihistamine)，作为口服活性组胺H1受体(histamineH1-receptor)和血清素拮抗剂。Hydroxyzinedihydrochloride具有抗焦虑作用，可用于广泛性焦虑障碍的研究。REFERENCES[1].Minogiannis,P.,etal.,Hydroxyzineinhibitsneurogenicbladdermastcellactivation.IntJImmunopharmacol,1998.20(10):p.553-63.1/2 MasterofBioactiveMolecules—您身边的抑制剂大师www.MedChemEMorichi,R.andG.Pepeu,Astudyoftheinfluenceofhydroxyzineanddiazepamonmorphineantinociceptoionintherat.Pain,1979.7(2):p.173-80.NikitaShekharSawantdesai,etal.Evaluationofanxiolyticeffectsofaripiprazoleandhydroxyzineasacombinationinmice.JBasicClinPharm.2016Sep;7(4):97-104.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792Fax: