第五讲 SCI收录我国三种医学杂志课件

LecturesonWritingMedicalPaperAbstractsinEnglish第五讲SCI收录我国三种医学杂志第五讲

SCI

收录我国三种医学杂志英文摘要赏析

SCI是美国《科学引文索引》（ScienceCitationIndex）的缩写。由于SCI数据库具有学科全面、学术影响大、覆盖国家广泛等特点，因而被其收录检索的期刊和论文分别被称作国际主流期刊和国际主流科学。刊物或论文被SCI收录和引用在一定程度上反映了该刊物或论文具有较高的学术水平和较大的国际影响力。我国目前被SCI收录的科技期刊共60种，而临床医学类只有中华医学杂志（英文版）、中国药理学报和世界胃肠病杂志3种。第五讲SCI收录我国三种医学杂志一、中国药理学报（ActaPharmacologicaSinica)Sample1

ActaPharmacologicaSinica2007February;28(2):238-245Effectofgenisteinonmouseblastocystdevelopmentinvitro

第五讲SCI收录我国三种医学杂志

AbstractAim:

1)Toexaminethecytotoxiceffectsofgenistein,anisoflavonecompound,onearlypostimplantationembryonicdevelopmentinvitro.Methods:2)Mouseblastocystswereincubatedinmediumwithorwithoutgenistein(25or50µmol/L)ordaidzein(50µmol/L)for24h.3)Cellproliferationandgrowthwasinvestigatedbydualdifferentialstaining,4)apoptosiswasanalyzedbyterminaldeoxynucleotidyltransferase-mediateddUTPnick-endlabeling(TUNEL)assay,and5)apoptoticornecroticcellswerevisualizedbyAnnexin-Vandpropidiumiodide(PI)staining.6)Implantationandpostimplantationdevelopmentofembryosweremeasuredbyinvitrodevelopmentanalysis第五讲SCI收录我国三种医学杂志

Results:

7)TUNELstainingandAnnexin-V/PIstainingshowedthatgenisteindose-dependentlyincreasedapoptosisinmouseblastocysts,whiledaidzein,anothersoyisoflavone,hadnosucheffect.8)Thepretreatmentoftheblastocystswithgenisteincausedfewercellsthanthecontrolgroupandthiseffectwasprimaryintheinnercellmass.9)Thegenistein-pretreatedblastocystsshowednormallevelsofimplantationonculturedishesinvitro,butsignificantlyfewergenistein-pretreatedembryosreachedthelaterstagesofembryonicdevelopmentversusthecontrols,withmanyoftheformerembryosdyingatrelativelyearlystagesofdevelopment.Inaddition,10)genisteintreatmentdecreasedthedevelopmentofmorulasintoblastocysts,anddietarygenisteinwasfoundtoinducecellapoptosisanddecreasecellproliferationinananimalassaymodelofembryogenesis.为主-动-宾-补(SVOC)结构的被动语态第五讲SCI收录我国三种医学杂志Conclusions:

11)Ourresultscollectivelyindicatethatgenisteintreatmentofmouseblastocystsinducesapoptosis,decreasescellnumbers,retardsearlypostimplantationblastocystdevelopment,andincreasesearly-stageblastocystdeathinvitro,whiledietarygenisteinappearstonegativelyaffectmouseembryonicdevelopmentinvivobyinducingcellapoptosisandinhibitingcellproliferation.12)Thesenovelfindingsprovideimportantnewinsightsintotheeffectofgenisteinonmouseblastocysts.第五讲SCI收录我国三种医学杂志Sample2Effectofnicotinamideonnewlydiagnosedtype1diabeticchildrenAbstract

Aim:Todeterminewhetheralowdoseofnicotinamide(NA)therapyforpediatricpatientswithtype1diabetes,initiatedwithinthefirst24hofdiagnosis,prolongsthe"honeymoon"periodandlowerstheirinsulinrequirements.第五讲SCI收录我国三种医学杂志

Methods:Allchildren(n=66)withnewlydiagnosedtype1diabetesadmittedtoSalmaniyaMedicalComplexbetween1998and2000,receivedNA1-2mg/kgperday,inadditiontoscinsulinbid.Thepatientswerefollowedfor24months(NAgroup).Findingsinthisgroupwerecomparedwithrecordsfromasimilarlydiagnosedcontrolgroup(n=37),whowereadmittedtothesamehospitalbetween1995and1997anddidnotreceiveNAtreatment.Theinsulindoseperkgbodyweightrequiredatbaselineandat3-monthlyintervalsupto2yearsafterdiagnosiswasdetermined.第五讲SCI收录我国三种医学杂志

Results:Atbaseline,thetwogroupsdidnotdifferwithrespecttoage,ethnicbackground,weight,insulindoseperkgbodyweightorglucoselevelsonadmission.However,NAgrouphadlowerinsulinrequirementsthancontrolgroupateach3-monthintervalupto2yearsafterdiagnosis.Conclusion:OurstudyresultssuggestthatevenlowdosesoforalNAgiventochildrenwithnewlydiagnosedtype1diabetesmayreduceinsulinrequirementsandprolongthe"honeymoon"period.第五讲SCI收录我国三种医学杂志范文赏析《中国药理学报》（ActaPharmacologicaSinica)的英文摘要具有以下特点：1）采用结构式英文摘要2）多用一般过去时和被动语态3）字数120～246，平均160字4）说明研究目的一般采用不定式5）文题均为名词短语，包括3种形式：①名词+介词短语，如of,in.名词前也可加修饰词；②名词+分词短语，现在分词或过去分词；③名词+不定式。

第五讲SCI收录我国三种医学杂志6）常用句型分别为：表示目的：Toinvestigate,Tostudy,Toexplore,Tosurveyandassess

表示方法：wasproposes,wererandomlydividedinto,wasdesignedby,weretestedby,wasmeasuredby,wasusedtodetect

表示结果：wasdetermined,wasdecreased,demonstrated,showed,wentupto,wassignificantlyhigher

表示比较：…ofAwas/werehigherthanthat/thoseofBAhassomesimilaritieswithB,TherewasnosignificantdifferencebetweenAandBNonsignificantdifferencewasfoundbetweenAandB(in…)

第五讲SCI收录我国三种医学杂志二、中华医学杂志英文版(ChineseMedicalJournal,CMJ)《中华医学杂志》英文版是中华医学会主办的综合性医学学术期刊，是中国历史最悠久的医学杂志。该杂志重点报道我国医学各学科最新进展和高水平科研成果，以及临床各科诊疗经验，是我国医学交流的重要窗口。目前该刊物被国内外10个重要生物医学数据库、检索系统和文摘期刊收录。ChineseMedicalJournal全球发行，作为医学会会刊和全世界50余个国家和地区建立交换项目。第五讲SCI收录我国三种医学杂志Sample1CalpainIinhibitionpreventsatrialstructuralremodelinginacaninemodelwithatrialfibrillation

XUEHong-jie,LIWei-min,LIYue,GONGYong-tai,YANGBao-feng,JINCheng-luo,SHENGLi,CHUShan,ZHANGLi,SHANHong-bo,LIUJieKeywords:atrialfibrillation·structuralremodeling·calpain·inhibitor·N-acetyl-leu-leu-metAbstract:Background

Atrialfibrillation(AF)isaccompaniedbyatrialstructuralremodeling.CalpainactivityisinducedduringAF.Totestacausalrelationshipbetweencalpainactivationandatrialstructuralchanges,N-acetyl-Leu-Leu-Met(ALLM),acalpaininhibitor,wasutilizedinacanineAFmodel.第五讲SCI收录我国三种医学杂志Methods

Fifteendogswererandomlydividedinto3groups:sham-operatedgroup,controlgroupandcalpaininhibitorgroup;eachwith5dogs.SustainedAFwasinducedbyrapidrightatriumpacingat600beatsperminutefor3weeks.ALLMwasadministeredatadosageof1.0mg∙kg-1∙d-1inthecalpaininhibitorgroup.Threeweekslater,theproteolysis,proteinexpressionofTnTandmyosin,calpainIlocalizationandexpressionandstructuralchangeswereexaminedinleftatrialfreewalls,rightatrialfreewallsandtheinteratrialseptumrespectively.Atrialsizeandcontractilefunctionwerealsomeasuredbyechocardiography.第五讲SCI收录我国三种医学杂志Results

Long-termrapidatrialpacinginducedmarkedstructuralchangessuchasenlargedatrialvolume,myolysis,degradationofTnTandmyosin,accumulationofglycogenandchangesinmitochondrialshapeandsize,whichwereparalleledbyanincreaseincalpainactivity.Thepositivecorrelationbetweencalpainactivityandthedegreeofmyolysis(rs=0.90961,P<0.0001)wasdemonstrated.Inadditiontostructuralabnormalities,pacing-inducedatrialcontractiledysfunctionwasobservedinthisstudy.Thepacing-inducedatrialstructuralalterationsandlossofcontractilitywerepartiallypreventedbythecalpaininhibitorALLM.第五讲SCI收录我国三种医学杂志

Conclusions

Activationofcalpainrepresentskeyfeaturesintheprogressiontowardsovertstructuralremodeling.Calpaininhibitor,ALLM,suppressedtheincreasedcalpainactivityandreversedstructuralremodelingcausedbysustainedatrialfibrillationinthepresentmodel.CalpaininhibitionmaythereforeprovideapossibilityfortherapeuticinterventioninAF.第五讲SCI收录我国三种医学杂志三、WorldJGastroenterol（世界胃肠病学杂志）

《世界胃肠病学杂志》（WorldJournalofGastroenterology,WJG)已被SCI、IM、CA、EM等国际检索系统收录。WJG主要报道食管癌、胃癌、肝癌、大肠癌、病毒性肝炎等原始论文，同时还设置文献综述、基础研究和临床研究栏目，对促进国内外胃肠病学信息的交流及学科的发展有着重大的意义。第五讲SCI收录我国三种医学杂志Sample1CorrelationofATP7BgenotypewithphenotypeinChinesepatientswithWilsondisease.AIM:TodeterminethemutationalcharacterizationofP-typeATP7BgeneandtoexplorethecorrelationofATP7BgenotypetophenotypeinChinesepatientswithWilsondisease(WD).METHODS:Seventy-fivepatientswithWDfrom72no-kinshipfamilies,44malesand31females,wereenrolledinthisstudy.Theageofonsetrangedfrom4to39years,<=18yearsin72patients.SomeexonsofATP7BgenemutationswereanalyzedinpatientswithWDbyusingbiochemicalmethods,polymerasechainreaction-singlestrandconfigurationpolymorphism(PCR-SSCP)andDNAsequenceanalysis.Atotalof778codingregionswereidentifiedwithrestrictionenzymeMspI.TheactivityofCu-ATPasewasassessedbymeasuringinorganicphosphorus.

第五讲SCI收录我国三种医学杂志RESULTS:Sixty-sixof75patients(88%)hadwithhepaticmanifestations,39ofthemhadonlyhepaticmanifestations,27patientshadhepaticandneurologicalmanifestationsorothersymptomsatthesametime(16patientshadassociatedneurologicalmanifestation,3patientshadosteopathy,8patientshadothersymptoms).Eightofthe75patie