【《高血压药物处方分析》8300字（论文）】

目录[21]中提到对于降压药物的选择上采用的原则为血压小于160/100mmHg的采用单一药物治疗，在2-4周治疗后未达标就两种药物联合。两种药物联合一般采纳ACEI或ARB类药物加上CCB类药物，如缬沙坦胶囊联合苯磺酸氨氯地平片；利尿剂加上ACEI或ARB类药物，如缬沙坦胶囊联合螺内酯片；CCB类药物加上利尿剂，如呋塞米片联合苯磺酸氨氯地平片；β受体阻滞剂加上CCB类药物，如琥珀酸美托洛尔缓释片联合苯磺酸氨氯地平片。如2-4周仍未达到标准阈值，则进行三种药物联合ACEI和ARB与CCB类药物与β受体阻滞剂联合或合ACEI和ARB与CCB类药物与利尿剂联合。参考文献参考文献[SEQ文献\*ARABIC1]RobertsJM,LindheimerM,PearsonG,etal.SummaryoftheNHLBIWorkingGrouponResearchon.[J].Hypertension:AnOfficialJournaloftheAmericanHeartAssociation,2003,41(3):437-445.[SEQ文献\*ARABIC2]TsengYuan-Fu,LinHsiu-Chen,ChaoJaneChen-Jui,etal.CalciumChannelblockersareassociatedwithreducedriskofParkinson'sdiseaseinpatientswithhypertension:Apopulation-basedretrospectivecohortstudy[J].JournaloftheNeurologicalSciences,2021,424[SEQ文献\*ARABIC3]ContaldiElena,MagistrelliLuca,MilnerAnna,etal.PotentialprotectiveroleofACE-inhibitorsandAT1receptorblockersagainstlevodopa-induceddyskinesias:aretrospectivecase-controlstudy[J].NeuralRegenerationResearch,2021,16(12):2475-2478.[SEQ文献\*ARABIC4]LiuRuru,MiBaibing,ZhaoYaling,etal.Gender-specificassociationbetweencarbohydrateconsumptionandbloodpressureinChineseadults[J].BMJNutrition,Prevention&Health,2021[SEQ文献\*ARABIC5]NaryzhnayaNatalia,KurbatovBoris,GorbunovAlexander,etal.Highcarbohydratehighfatdietinducestheproductionofconnectivetissuegrowthfactors,increasedbloodpressure,andchangesintheaorticwallinagedrats[J].TheFASEBJournal,2021,35[SEQ文献\*ARABIC6]YankeyBarbaraA,RothenbergRichard,StrasserSheryl,etal.Effectofmarijuanauseoncardiovascularandcerebrovascularmortality:AstudyusingtheNationalHealthandNutritionExaminationSurveylinkedmortalityfile[J].EuropeanJournalofPreventiveCardiology,2017,24(17):1833-1840.DOI:10.1177/2047487317723212.[SEQ文献\*ARABIC7]KaraSonatPınar,OzkanGulsum,YılmazAhsen,etal.MicroRNA21andmicroRNA155levelsinresistanthypertension,andtheirrelationshipswithaldosterone.[J].RenalFailure,2021,43(1):676-683.[SEQ文献\*ARABIC8]何玉雯.两种剂量苯磺酸氨氯地平治疗高血压的临床效果比较[J].临床合理用药杂志,2019,12(13):53-54.DOI:10.15887/ki.13-1389/r.2019.13.027.[SEQ文献\*ARABIC9]何文文,何美青.苯磺酸氨氯地平和苯磺酸左旋氨氯地平治疗高血压的效果对比[J].中国生化药物杂志,2017,37(8):193-194.DOI:10.3969/j.issn.1005-1678.2017.08.079.[SEQ文献\*ARABIC10]王士强,唐杨章,张怀金等.硝苯地平控释片治疗老年单纯性收缩期高血压的临床研究[J].中国临床药理学杂志,2017,33(14):1298-1300.DOI:10.13699/ki.1001-6821.2017.14.003.[SEQ文献\*ARABIC11]周欣满.缬沙坦治疗轻中度高血压疗效及安全性评价[J].中国药业,2016,25(23):50-52,53.[SEQ文献\*ARABIC12]王国锋,韩硕,王琦等.琥珀酸美托洛尔缓释片治疗原发性高血压临床疗效观察[J].中国血液流变学杂志,2020,30(1):50-52.DOI:10.3969/j.issn.1009-881X.2020.01.010.[SEQ文献\*ARABIC13]郑世路,王春雷,迟玉霞等.美托洛尔治疗高血压的用药剂量分析[J].医学信息（下旬刊）,2013,26(12):637.[SEQ文献\*ARABIC14]殷莉.小剂量β-受体阻滞剂治疗老年性高血压导致严重心动过缓[J].重庆医学,2004,33(2):268-269.DOI:10.3969/j.issn.1671-8348.2004.02.052.[SEQ文献\*ARABIC15]王杜娟.缬沙坦联合酒石酸美托洛尔治疗老年高血压的临床探究[J].当代医学,2017,23(12):101-103.DOI:10.3969/j.issn.1009-4393.2017.12.050.[SEQ文献\*ARABIC16]朱春燕.苯磺酸氨氯地平(络活喜)与缬沙坦(代文)联合治疗高血压的疗效分析[J].健康必读,2019,(6):93-94.[SEQ文献\*ARABIC17]张进美.苯磺酸氨氯地平联合酒石酸美托洛尔治疗顽固性高血压的临床疗效[J].中外女性健康研究,2020,(21):53-54.[SEQ文献\*ARABIC18]管红斌,何凯平,桓文穆等.螺内酯联合缬沙坦对高血压早期肾损害患者尿微量白蛋白及肾功能的影响[J].国际医药卫生报,2019,25(9):1420-1423.DOI:10.3760/cma.j.issn.1007-1245.2019.09.019.[SEQ文献\*ARABIC19]林永阳.高血压患者联合用药的合理性与不良反应特点及联合用药禁忌证[J].临床合理用药杂志,2018,11(18):105-106.DOI:10.15887/ki.13-1389/r.2018.18.051.[SEQ文献\*ARABIC20]杨华.高血压患者联合用药的禁忌[J].中西医结合