Norzine-dimalate-Thiethylperazine-dimalate-生命科学试剂-MCE

Hotline:400-820-3792Inhibitors•ScreeningLibraries•Proteinswww.MedChemENorzinedimalateCat.No.:HY-A0188CASNo.:52239-63-1Synonyms:Thiethylperazinedimalate分⼦式:C₃₀H₄₁N₃O₁₀S₂分⼦量:667.79作⽤靶点:DopamineReceptor;HistamineReceptor;Bacterial;Amyloid-β;DrugDerivative作⽤通路:GPCR/GProtein;NeuronalSignaling;Immunology/Inflammation;Anti-infection;Others储存⽅式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY⽣物活性Norzinedimalate(Thiethylperazinedimalate)⼀种Phenothiazine(HY-Y0055)衍⽣物，⼀种⼝服有效的多巴胺D2受体和组胺H1受体拮抗剂。Norzinedimalate也⼀种选择性的ABCC1激活剂，可减少⼩⿏中的淀粉样β(Aβ)负荷。Thiethylperazine具有⽌吐，抗精神病和抗作⽤。IC50&TargetH1ReceptorD2Receptor户使⽤本产品发表的科研⽂献•ACSEnvironAu.2025Aug8.•AnalChem.2025Jun3;97(21):11099-11109.Seemorecustomervalidationsonwww.MedChemEREFERENCES[1].CzeizelAE,etal.Case-controlstudyofteratogenicpotentialofthiethylperazine,ananti-emeticdrug.BJOG.2003May;110(5):497-9.[2].KrohnM,etal.Cerebralamyloid-βproteostasisisregulatedbythemembranetransportproteinABCC1inmice.JClinInvest.2011Oct;121(10):3924-31.[3].RahbarM,etal.Enhancementofvancomycinactivitybyphenothiazinesagainstvancomycin-resistantEnterococcusfaeciuminvitro.1/2MasterofBioactiveMolecules—您⾝边的抑制剂⼤师www.MedChemEBasicClinPharmacolToxicol.2010Aug;107(2):676-9.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792ax: