Ocaperidone-Standard-生命科学试剂-MCE

Hotline:400-820-3792Inhibitors • ScreeningLibraries • Proteinswww.MedChemEOcaperidone(Standard)Cat.No.:HY-101094RCASNo.:129029-23-8分子式:C₂₄H₂₅FN₄O₂分子量:420.48作用靶点:5-HTReceptor;ReferenceStandards;DopamineReceptor作用通路:GPCR/GProtein;NeuronalSignaling;Others储存方式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY生物活性Ocaperidone(Standard)是Ocaperidone(HY-101094)的分析标准品。本产品用于研究及分析应用。Ocaperidone是一种有效的安定剂，为5-HT2和多巴胺D2的拮抗剂，5-HT1A的激动剂，对5-HT2，a1-adrenergic受体，dopamineD2，组胺HIC50&TargetKi:0.14nM(5HT2),0.46nM(a1-adrenergicreceptor),0.75nM(DopamineD2),1.6nM(HistamineH1),5.4nM(a2-adrenergicreceptor)[1]pEC50:7.60(h5-HT1A)[2]pKi:8.08(h5-HT1A)[2]REFERENCESLeysenJE,etal.Invitroandinvivoreceptorbindingandeffectsonmonoamineturnoverinratbrainregionsofthenovelantipsychoticsrisperidoneandocaperidone.MolPharmacol.1992Mar;41(3):494-508.CosiC,etal.Agonist,antagonist,andinverseagonistpropertiesofantipsychoticsathumanrecombinant5-HT(1A)receptorsexpressedinHeLacells.EurJPharmacol.2001Dec14;433(1):55-62.RijndersHJ,etal.Thediscriminativestimuluspropertiesofbuspironeinvolvedopamine-2receptorantagonistactivity.Psychopharmacology(Berl).1993;111(1):55-61.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792Fax:021