Osteocalcin-human-TFA-Osteocalcin-1-49-human-TFA-生命科学试剂-MCE

Hotline:400-820-3792Inhibitors•ScreeningLibraries•Proteinswww.MedChemEOsteocalcin(human)TFACat.No.:HY-P2588ASynonyms:Osteocalcin(1-49)(human)TFA分⼦式:C₂₆₉H₃₈₁N₆₇O₈₂S₂·xC₂HF₃O₂Sequence:Tyr-Leu-Tyr-Gln-Trp-Leu-Gly-Ala-Pro-Val-Pro-Tyr-Pro-Asp-Pro

-Leu-{Gla}-Pro-Arg-Arg-{Gla}-Val-Cys-{Gla}-Leu-Asn-Pro-Asp-

Cys-Asp-Glu-Leu-Ala-Asp-His-Ile-Gly-Phe-Gln-Glu-Ala-Tyr-Arg

-Arg-Phe-Tyr-Gly-Pro-Val(Disulfidebridge:Cys23-Cys29)SequenceShortening:YLYQWLGAPVPYPDPL-{Gla}-PRR-{Gla}-VC-{Gla}-LNPDCDELADHIGFQEAYRRFYGPV(Disulfidebridge:Cys23-

Cys29)作⽤靶点:EndogenousMetabolite作⽤通路:MetabolicEnzyme/Protease储存⽅式:Sealedstorage,awayfrommoisturePowder-80°C2years-20°C1yearInsolvent-80°C6months-20°C1monthBIOLOGICALACTIVITY⽣物活性Osteocalcin(Osteocalcin(1-49))(human)TFA⼀种依赖维⽣素K的⾻特异性蛋⽩。Osteocalcin(human)TFA对⾻重塑表常见的⼏种细胞类型具有趋化作⽤。REFERENCES[1].KuronenI,etal.Productionofmonoclonalandpolyclonalantibodiesagainsthumanosteocalcinsequencesanddevelopmentofatwo-siteELISAforintacthumanosteocalcin.JImmunolMethods.1993Aug9;163(2):233-40.[2].MundyGR,etal.Chemotacticactivityofthegamma-carboxyglutamicacidcontainingproteininbone.CalcifTissueInt.1983;35(2):164-8.[3].ColfordJW,etal.Immunoradiometricassayforintacthumanosteocalcin(1-49)withoutcross-reactivitytobreakdownproducts.ClinChem.1999Apr;45(4):526-31.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792ax: