抗生素ppt课件（英文精品）antibiotic use data the long way from numbers to

Antibiotic use data: the long way from numbers to knowledge Nico Bondt LEI, part of Wageningen UR International conference 15 november 2011 Content presentation n Antibiotic usage in perspective n Objective for collection of antibiotic use data n Monitoring in Europe and the Netherlands n How to measure usage n Trends in the Netherlands and Europe n Example of country comparison n Conclusions Antibiotic usage in perspective - quantity n Outpatient human use in Europe: 1 to 3% (ECDC) n Animal production Netherlands (LEI, 2011): n Exposure pigs Jensen et al, 2004) l insight into antibiotic use per species l dosage according to summ. of product characteristics? l average live weight or weight at treatment? Total sales in the Netherlands (gram per kg; FIDIN) Estimated exposure NL per species (dd/ay; LEI) www.maran.wur.nl Sales patterns NL mg/kg): + 118% n estimated exposure (NL): + 83% n estimated exposure per animal species (NL): lpigs + 33% lcattle + 100% lveal calves - lpoultry + 475% + 40 - 50% Conclusions about total sales data n Total sales data: usable numbers, rough knowledge! n Start collecting data per species l information per species needed to gain insight into exposure & risk l differences between species more important than between countries n Publications about total sales need improvement l avoid oversimplified comparisons based on total sales data NL - DK: relatively similar animal demographics, but still difficult to compare l careful communication: “mg/kg” easily misinterpreted l take into account sa