妊娠高血压疾病产妇分娩前后血液流变学变化研究.doc

妊娠高血压疾病产妇分娩前后血液流变学变化研究 许艳蕾1米梅艳1崔富春1李红艳1孙莉2 1.石家庄市第四医院妇产科，河北石家庄050011；2.白求恩国际和平医院，河北石家庄050011 摘要目的探讨妊娠高血压疾病产妇分娩前后血液流变学的变化。方法选取xx年1月xx年2月本院收治的120例妊娠高血压患者为研究对象（观察组），另外选取同期本院的120例正常产妇为对照组，检测并比较两组患者产前及产后1、3d血液流变学的变化情况。结果观察组患者产前及产后1、3d时的血浆黏度、全血低切黏度、全血低切还原黏度以及红细胞聚集指数、红细胞刚性指数均高于对照组，差异有统计学意义（P0.05）；观察组产后1、3d时的血浆黏度、全血低切黏度、全血低切还原黏度以及红细胞聚集指数、红细胞刚性指数均均低于产前，差异有统计学意义（P0.05）。结论妊娠高血压产妇的血流存在异常，各血液流变学指标均高于正常产妇，且分娩前后血液流变学呈持续性变化。 关键词妊娠高血压；血液流变学；分娩前后 R714.246A1672-5654（xx）06（c）-0009-02 Researchthechangesofhemorheologyinthematernalwithpregnancy-inducedhypertensiondiseasebeforeandafterthepuerperachildbirth XUYanlei1MIMeiyan1CUIFuchun1LIHongyan1SUNLi2 1.Unitsanddepartments：DepartmentofObstetricsandGynecology,thefourthhospitalofShijiazhuangCity，Hebei050011,China;2.BethuneinternationalHepingHospital,Hebei050011,China AbstractObjectiveToexplorethechangesofhemorheologyinthematernalwithpregnancy-inducedhypertensiondiseasebeforeandafterthepuerperachildbirth.Methods120maternalwithpregnancy-inducedhypertensiondiseasewereselectedastheresearchobject(observationgroup)inourhospitalfromJanuaryxxtoFebruaryxx,Inaddition,120casesofnormalwomenwereselectedascontrolgroupinthesameperiodinourhospital,thechangeofbloodrheologyinprenatalandpostnatal1,3dintwogroupsweretestedandpared.ResultsThewholebloodlowshearviscosity,plasmaviscosity,wholebloodlowshearreductionviscosityanderythrocyteaggregationindex,erythrocyterigidityindexinobservationgroupprenatalandpostnatal1,3dwerehigherthanthoseincontrolgroup,thedifferencewasstatisticallysignificant(P0.05).Thewholebloodlowshearviscosity,plasmaviscosity,wholebloodlowshearreductionviscosityanderythrocyteaggregationindex,erythrocyterigidityindexinobserva