益生菌在消化系肿瘤治疗中的潜在应用价值.doc

益生菌在消化系肿瘤治疗中的潜在应用价值 刘斌 湖南省涟源市人民医院肿瘤内科，湖南涟源417100 摘要目的研究并探讨益生菌在消化系肿瘤临床治疗中的潜在价值与效果。方法择取该院自xx年1月xx年6月期间，住院部所收治胃癌患者共计50例为研究对象，随机分为对照组、干预组，每组25例。对照组常规治疗，干预组加双歧杆菌活菌肠溶胶囊治疗。对两组患者特异性组织学、免疫组化指标进行对比分析。结果干预组在益生菌干预下的微脓疡、纤维组织增生症状得到明显改善，优于对照组；癌组织微血管密度指标以及增值细胞核抗原指标均明显低于对照组，数据对比差异有统计学意义（P0.05）。结论双歧杆菌可抑制胃癌患者组织血管新生，改善缺血性问题，降低癌细胞增殖活性，效果突出。 关键词双歧杆菌；胃癌；增殖活性 R738.992A1674-074（4）07（c）112-02 PotentialApplicationValueofProbioticsintheTreatmentofTumorofDigestiveSystem LIUBin DepartmentofMedicalOncology，HunanLianyuanPeoplesHospital，Lianyuan，HunanProvince，417100，China AbstractObjectiveTostudyandexplorethepotentialvalueandeffectofprobioticsinthetreatmentoftumorofdigestivesystem.Methods50patientswithgastriccanceradmittedinthein-patientdepartmentofourhospitalfromJanuaryxxtoJunexxwereselectedasthesubjectsandtheywererandomlydividedintothecontrolgroupandtheinterventiongroupwith25casesineach.Thecontrolgroupwasgiventheconventionaltreatment，andtheinterventiongroupwasgiventheconventionaltreatmentplusbifidobacteriumentericcoatedcapsules.Thespecifichistologicalandimmunohistochemicalindicatorsofthesetwogroupswereparedandanalyzed.ResultsAftertheinterventionofprobiotics，thesymptomsofmicroabscessandfibroustissuehyperplasiaoftheinterventiongroupwereimprovedsignificantly，whichwerebetterthanthoseofthecontrolgroup；carcinomamicrovesseldensityindexandproliferatingcellnuclearantigenindexeswereobviouslylowerthanthoseofthecontrolgroup，therewas