胶质母细胞瘤解析ppt课件.ppt

CasereportXiancentralhospitalDangshan Newwords somnolentia s mn len r 嗜睡morphology m r f l d i 形态学paediatric pi d tr k 儿科的hydrocephalus ha dr sef l s 脑积水heterogeneous成分混杂的cauliflower菜花neuroepithelial神经上皮的prognosis预后infiltrate浸润渗透 Medicalhistory 2 year oldmalepatientSomnolentia decreaseconsciousness3hours AEpendymomaBChoroidplexuspapillomaCIntraventricularmeningiomaDGlioblastoma Whatisyourdiagnosis Pathologicalresult LateralventricleglioblastomaImmunohistochemistry GFAP S 100 Vim Synpart Ki6740 Olig 2few CD99 NeuN CK EMA Glioblastoma Incidence Glioblastomaaccountsforabout5 7 ofallbraintumorsinchildrenPeakage 45 55yearsoldlessoccuratagelowerthan30 year oldLocation Supratentorialwhitemattermostcommon especiallyinfrontalandtemporallobes Morphology Poorly marginated diffusely infiltratingnecroticmass TumortypicallyacrosseswhitemattertractstoinvolvecontralateralhemispherePrognosis Poor 1yearsurvivalrateisonlyabout50 NECTFinding Irregularisodenseorhypodensemasswithcentralhypodensityrepresentingnecrosis Markedmasseffectandsurroudingedema tumorinfiltration hemorragenotuncommon calcificationrareCECTFinding 95 havestong heterogeneous irregularrim enhancement T1WIirregularisotense hypointensewhitemattermassT2WIheterogeneous hypointensemasswithadjacenttumorinfiltrationandedemaDWInotypicallydiffusionrestrictionnecrosis cysts hemorragemaybeseen MRFinding Ependymoma Peakage beforetheageof5yearsoldLocation about8 occuredinthelateralventricleMorphology typicallyheterogeneousmass withareasofnecrosis calcification cysticchangeandfrequenthemorrhageMRFinding T1WIisointensetohypointenserelativetowhitematterT2WIhyperintensetowhitematterT1C Gd enhancementpresentbutheterogeneousDWIdiffusionrestrictmaybeseeninsolidcomponents CTEpendymoma MREpendymoma Anuncommon benignneuroepithelialintraventriculartumourwhichcanoccurinboththepaediatricandadult lobulatedorcauliflower likemasseshydrocephaluscommonCTiso orsomewhathyperdense homogeneousenhancement T1WItypicallyisointenseorsomewhathypointense T2WIisotohyperintense T1C Gd markedenhancement tendstobehomogenous Choroidplexuspapilloma T2WIT1WI T1C Choroidplexuspapilloma Intraventricularmeningioma Location 80 trigoneoflateralventricle 15 thethirdventricle 5 thefourthventricle CT60 slightlyhyperdensetonormalbrain 20 30 havesomecalcification 72 brightlyandhomogenouslycontrastenhance lessfrequentinmalignantorcysticvariants T1WIisointenseorsomewhathypointensecomparedtogreymatter T2WIisointense hy