脑外伤读书报告.doc

11-2111114105.21-.1. 1nscsscie14-17dnscse14-17dnscs2 66 feeney 60 24 h3 1 ml dmem/f12 11010 l-1 +11010 l-1 30 mg/kg 1 /d3 d2. pnh123pnh-t-a8108/kgcd34+1.45106/kgpnh3. 1) wistar232-325+ msc(ami) 30minmsc ( 1106 /0.1ml msc10 )ami ( pbs 0.1ml10)(sham 5 )72h 2) nyha363617192;1,324h99mtespect.ipnh 1 0.4%2.0%10%21. 1.1. 3 41.2. 5 6 72. 2.1. 82.2. 92.3. 3 10:1.j.,2011,24(12).2.m.:,2001:455-467.3,.j.,2007,36(12):1072.4angele mk,frantz mc,chaudry ih.gender and sex hormones influence the response to trauma and sepsis:potential therapeutic approaches.clinics,2006,61(5):479-488.5,.,2008,4:74.6,.,2010,14(1):48.7.,2011,6(36):236.8,.,2011,1a:40-41.9,.,2010,1(22):16-18.10.j.2010,17(7):149-150.12345 2011bmp)2011-12-01 bone regeneration: current concepts and future directionsbmp) bmp - 27fac-tor-b- 1b-tcpbone regeneration:current concepts and future directions bmpbmp-1-transforming growth factortgf-24 bmp30000da, bmp400,40%50%tgf-bmp,bmp,bmp2,2 , ,bmp40 , bmp 15 , -(transforming growthfactor2,tgf2) , , bmp , bmp224 ,bmp25678 , - 5(growth and differentiationfactor ,gdf25) gdf26(bmp213) gdf27(bmp212) ,bmp23 gdf210(bmp23b) , bmp24 ,424(1) bmp-4 ,bmp-4 tgf2 , - (bmpr ) , bmp (bmpr , alk2 , alk3 , alk6) bmpr bmpr , bmpr , smad1smad5smad8 ,smads smad4 ,(2) bmp-4 bmp , bmp24 chordin noggin , ,2,3 ; bmp-4 tolloid ,chordinbmp-4 , bmp24 (hspgs) ,bmp-4 ; bmp-4follistatin , bmp , ; bmp-4 ep45 , ep45 bmp-4 ,bmp-4 , bmp smad6smad7 ,; bmp bambi , bambi , tgf2 , ,bmps ;bmp - smurf ,bmp , sno ski ,bmp , , bmp ; smads , tak1bmp ,bmp 3bmp-4 bmp-4 ,bmp-4 , , bmp-4 , bmp-4 , bmp-4 ,bmp-4 , bmp-4 , bmp-4 fang bmp-4 , , , , bmp-4 , , bmp-4 cdna ,bmp-4mfg bmp-4 , , chen , bmp-4 4bmp-4 bmp-4(fibrodysplasia ossificans progressiva , fop) kaplan fopbmp24 mrna , , bmp24 , bmp-4 bmp nogginfollistatingremlin ,bmp-4 , bmp-4 , fop ,bmps , bmp24dna ,bmp24 , bmp-4 , cushingsbmp24 att220 acth 2bmp-2bmps1988bmp-2 30kds301816kds30kdsbmp-2bmp-2(rh bmp-2)rhbmp-2bmp-21