可逆性后部脑病综合征

Reversible posterior encephalopathy syndrome,可逆性后部脑病综合征,Reversible posterior encephalopathy syndromereversible posterior leukoencephalopathy syndrome reversible posterior cerebral edema syndrome,Clinical Findingsneurologic abnormalities,Headachedecreased alertness altered mental functionvisual lossstuporseizures,Common location of PRES,Common location of PRES,Parietal-occipital most commonPosterior frontal TemporalThalamusCerebellumBrainstemBasal ganglia,Case1： A Reversible Posterior Leukoencephalopathy Syndrome （N Engl J Med. 1996 Feb 22;334(8):494-500. ）,Several risk factors of PRES,hypertensive encephalopathychronic renal insufficiencyblood transfusionEclampsiaimmunosuppressive drugsintravenous immunoglobulin (IVIg) treatmentpost-transplantation stage in liver diseaseacute phases of autoimmune disorders,Etiology of PRES,Case2：Reversible posterior encephalopathy syndrome due to intravenous immunoglobulin in a child with GBS,MRI examination of the brain. Axial FLAIR T2 at day 5 after completing IVIg,One week after first MRI,J Pediatr Neurosci. 2011 Jul-Dec; 6(2): 138140.,血管源性水肿.Vasogenic edema,Case3：Posterior reversible encephalopathy syndrome (PRES) and CT perfusion changes,MRI images in PRES,Int J Emerg Med. 2012; 5: 12.,Case3：Posterior reversible encephalopathy syndrome (PRES) and CT perfusion changes,Int J Emerg Med. 2012; 5: 12.,Case 4： Posterior Reversible Encephalopathy Syndrome Mimicking a Left Middle Cerebral Artery Stroke,Initial Head CT without contrast showed no evidence of acute left middle cerebral infarct or hemorrhage but showed subcortical white matter hypodensity with slight mass effect in bilateral posterior frontal, parietal, occipital, and temporal lobes most consistent with vasogenic edema.,Case 4： Posterior Reversible Encephalopathy Syndrome Mimicking a Left Middle Cerebral Artery Stroke,Open Neuroimag J. 2012; 6: 1012.,Comparison of magnesium sulfate and mannitol in treatment of eclamptic women with posterior reversible encephalopathy syndrome,AbstractOBJECTIVE: To evaluate and compare the effectiveness of magnesium sulfate (MgSO(4) and mannitol in the treatment of posterior reversible encephalopathy syndrome (PRES) in eclamptic women.STUDY DESIGN: This retrospective analysis includes 62 eclamptic women between 22 and 40weeks of gestation who were diagnosed with PRES in a tertiary care center. To treat neurological symptoms, 34 women received magnesium sulfate (Group 1) and the remaining 28 received 20% mannitol (Group 2) at the discretion of treating physician.RESULTS: Ten patients from both Group 1 (29%) and Group 2 (35.7%) were normotensive at admission. 59 of 62 patients presented with seizure. All patients underwent fluid attenuated inversion recovery (FLAIR) magnetic resonance imaging (MRI). Parietooccipital region and cerebellum were the most commonly affected areas. The duration of treatment was significantly shorter in Group 1 than Group 2 (p0.001). Neurological examinations and the recovery after treatment were significantly better in favor of MgSO(4) group (p=0.039).CONCLU