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1注射用尖吻蝮蛇凝血酶单次给药耐受性及安全性研究A1A0A2A3A4A5A6A7A8A9A10A11A12A13A14A15A16A17A18A19A20A21A11A22A23A24A25A26A27A28A25A29A30A31A3230A33A34A25A35A36A37A38A24A39A40A41A42A43A44A30A31A45A46A4705UA481UA482UA483UA264UA49A50A51A52A53A54A55A56A57A58A59A60A61A62A63A56A24A39A40A64A65A241A56A59A60A62A39A66A67A68A59A60A69A70A59A60A71A67A72A73A62A39A66A74A75A76A77A78A79A24A39A40A22A80A81A20A82A26A83A84A85A86A87A88A89A48A90A91A92A24A39A40A22A17A93A94A48A95A93A94A48A16A17A96A97A48A17A98A99A100A101A48A102A96A48A103A96A48A84A104A105A48A17A80A44A106A107A108A29A109A110A3205A1114UA59A60A24A39A40A112A97A23A24A62A113A114A115A116A117A104A18A118A48A113A114A115A116A118A119A60A48A17A120A121A122A123A124A87A88A90A125A126A127A128A62A129A130A131A132A107A108A133A87A88A90A134A135A136A100A44A29A109A137A32A9A10A11A12A13A14A15A16A17A18A52A138A59A60A13305A1114KUA139A27A28A22A29A140A141A142A141A142A143A144A145A146A147A148A149A150A151A152A153A154A155A156A157A158A143A144A145A146A147A148A149A159A160A161A162A163A164A165A166A167A168A169A170A171A161A162A172A173A174A175A176A177A178A179A180A181A167A168A182A183A184A185A186A187A188A189A190A191A192A193A194A195A191A196A191A197A190A198A199A200A201A202A191A203A204A205A188A206A207A208A209A196A210A211A212A197A190A186A213A214A215A202A191A188A212A216A217A218A219A220A221A193A222A201A223A224A225A226A227A228A209A188A229A230A216A196A231A232A221A233A234A202A191A188A235A236A216A237A229A230A216A238A199A196A239A240A186A213A241A242A243A244A245A246A219A247A248A249A250A251A252A248A249A251A252A247A253A247A254A255A250A14A0A236A238A191A192A23A1A209A2A3A4A5A6A207A7A8A9A10A47A139A11A12A13A191A15A203A144A182A183A16A17A196A193A18A19A196A196A197A20A21A199A22A22A24A193A193A22A193A52A219A247A253A25A26A27A28A29A28A29A33A30A31A216A236A238A32A24A22A34A196A202A35A47A199A36A37A199A206A207A37A199A52A208A196A209A38A47A193A207A39A37A24A206A211A37A39A52A212A40A196A227A41A47A207A22A37A211A206A215A37A211A52A216A42A196A227A41A43A44A47A199A193A37A199A36A206A22A37A211A215A52A45A236A238A32A46A48A49A100A49A101A50A207A51A53A54A49A221A55A53A54A56A57A45A207A58A59A49A93A58A59A49A6A207A60A61A49A207A51A62A63A190A49A100A60A49A101A60A49A82A64A65A49A207A16A189A49A48A82A81A49A225A66A104A46A67A58A45A238A199A68A193A228A196A229A69A209A70A191A211A196A238A199A68A211A71A72A73A196A229A74A75A224A76A191A211A77A78A238A199A45A46A237A79A49A239A80A47A241A199A22A242A19A243A52A49A244A209A191A211A104A83A205A45A46A191A211A70A132A84A196A248A70A132A227A65A45A249A85A86A87A42A49A249A88A89A90A216A219A225A91A92A234A64A94A238A199A95A96A237A191A211A188A191A197A97A212A98A208A209A172A196A236A238A32A99A102A103A105A106A107A108A109A110A219A247A253A111A14A112A113A114A113A114A115A209A116A117A118A119A77A78A238A199A219A24A22A34A236A238A32A120A116A117A189A95A96A92A121A122A22A37A215A216A18A49A193A216A18A49A199A216A18A49A24A216A18A237A211A216A18A123A71A124A108A125A126A127A196A128A127A207A34A219A238A199A129A218A125A126A130A38A125A126A131A129A221A233A196A133A203A91A92A134A135A68A193A127A188A229A230A216A50A235A236A216A136A137A172A196A138A140A141A142A246A193A127A188A143A191A219A247A253A145A146A254A251A252A147A148A149A150A151A251A252A147A148A150A151A128A71A236A238A32A133A74A75A193A71A125A126A127A188A238A199A196A143A191A95A96A220A152A153A154A23A196A238A199A155A156A236A238A32A225A157A155A77A78A238A199A57A158A159A160A161A162A219A238A199A155A156A163A164A165A166A236A238A32A188A16A167A227A168A47A227A169A49A153A170A49A207A171A49A173A239A52A237A48A82A81A45A143A191A172A36A199A174A208A225A66A226A175A45A143A191A68A237A143A191A172A199A211A174A49A36A199A174A226A175A236A238A32A188A207A58A59A49A93A58A59A49A6A207A60A61A49A207A51A62A63A190A49A100A60A49A101A60A49A82A64A65A49A207A16A189A104A43A176A21915A177A178A179A180A181A182A183A184A177A178A180A181A182A1832A185A186A187A188A189A190A191A192A194A195A198A200A201A203A204A205A210A213A214A217A218A219A220A222A223A204A205A224A227A230A231A232A230A233A234A235A233A234A236A238A240A245A246A247A250A251A252A253A254A255A22A253A0A1A4A219A220A222A223A230A234A53A77A54A219A220A222A223A254A55A55A246A247A230A56A235A89A2A2302A89A2A230A104A57A3A5A222A223A104A250A18A39A6A39A6A18A7A8A41A9A10A43A11A12A13A11A12A33A14A15A253A252A16A192A201A17A31A214A40A19A222A60A215A20A21A23A59A47A17A200A215A24A230A193A24A230A199A24A230A201A24A254A211A24A52A214A129A59A25A224A227A230A231A232A230A233A234A254A233A234A236A238A47A216A26A27A28A29A52A132A133A30A220A227A47A61A32A17A200A17A215A52A214A63A167A193A34A8A48A35A36A37A41A9A10A43A11A38A42A35A36A10A43A44SXA45NA466A4905U1U2U3U4UA50A51A58A62A6429334892583739273347224506722950771A65A66A58CMA641696762216367314169503511696745516933532A67A68A58KGA6462837035533186625056860174716100510A67A68A69A7021771182067091217720420901522125103A71A72A71A73A74A75A76A78A75A76A79A80A81A82A83A84A85A86A87A88A90A91A81A82A83A84A85A86A88A90A92A93A94A95A96A97A98A99A100A101A102A103A105A106A107A108A109A110A108A111A239A112A122A113A102A114A115A116A117A118A96A119A120A121A92A123A124A125A115A126A127A128A130A131A232A134A173A135A105A136A137A138A108A225A139A140A141A142A116A117A118A119A120A143A144A145A146A147A14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