On the beauty cosmetics（在美容化妆品）

1、 On the beauty cosmetics Abstract: brief reasons and synthesis mechanism of the formation of melanin, the types of cosmetic skin lightening products, skin lightening ingredients in cosmetics kinds of simple principle analysis. Prospect the future and the development trend of skin lightening cosmetic

2、s. Trend. Keywords: cosmetic whitening whitening mechanism outlook A. Whitening product demand along with the improvement of peoples living standards and the standards of beauty, white skin and Jie Yun growing majority of women are respected. Demand for whitening products have been enjoying a large

3、proportion, so far still the largest, and the pursuit of customer whitening products will enable the continuous development of the update. Has been the topic of skin lightening are people deeply concerned about people hope that through the use of whitening care products white, smooth skin, and some

4、functional whitening cosmetics to lighten age spots, melasma and other pigmentation. To relieve skin pigmentation troubles for whitening recipe design, medicine and aesthetics, it really works, if forming a mainstream. 1 II. Skin melanin formation mechanism of the development and application of the

5、whitening agent should be established based on in-depth understanding of the whitening mechanism, skin melanin inhibition mechanism is a central element of the whitening mechanism, therefore, to understand the causes and mechanism of the formation of melanin is the primary. Melanin production causes

6、 skin melanin production for a variety of reasons, such as ultraviolet light, exhaust gases, reactive oxygen species and other environmental factors. Certain foods is also the bane of the darkening of the skin, such as copper, iron, zinc and other metal-rich food is easy to make human skin darkening

7、, This is because these metals can be directly or indirectly increase the quantity and activity of tyrosinase activity dopaquinone other substances and melanin. many drugs will also change the normal color, such as chloroquine on melanoma particularly strong affinity, will add to the color black. ma

8、ny diseases can also alter the normal color it black, such as malnutrition, disease, oxidative and antioxidant imbalance; endocrine disorders; the microecology imbalance; metabolic disorders; body The content of trace elements such as abnormal 2. 2 melanin synthesis mechanism of skin melanin synthes

9、is steps: tyrosine intake, storage and distribution, synthesis and activity of tyrosinase, melanosomes of melanocytes and melanocyte dendrites the melanin granules transported to angle prion cells, keratinocytes, melanocytes particles move with the epidermal cells, accompanied by shedding of the str

10、atum corneum is discharged. 3 In the process of melanin synthesis, influenced by many factors, first is the activity of tyrosinase, the enzyme for copper-containing oxidase, its activity and copper ion content associated biochemical processes in the body and the change of the physical environment, t

11、he impact on the activity of tyrosinase. from tyrosine to dopa was converted to dopa, dopa quinone conversion by tyrosinase catalytic tyrosinase directly controls the starting and speed of melanin synthesis, decide whether the follow-up steps to be able to carry so when a variety of factors acting o

12、n tyrosinase its activity increases, an increase in melanin synthesis, tyrosinase activity was inhibited melanin synthesis to reduce 4,5. III. Cosmetic skin lightening can be divided into three categories of whitening category, whitening, and raise white class 6. 1 whitening products and its three t

13、ypical principle (1 cover: are physical methods. .80 Late 1990s pre-whitening powder honey in skin care products which add Khin white powder or similar white powder covering the surface of the skin by smearing the skin looks white whitening powder honey as a brand cosmetics rage. due to changes in c

14、onsumer habits and better alternatives such products almost be eliminated only a small number of evolved into makeup wet powder varieties. Added to the skin (exfoliative: make skin whiten the stripping method can be divided into two types of methods in physics: certain types of minerals, plants nut

15、shells, animal bones, shells and other classes crushed into a certain fineness massage supplies or grinding stripping agent is made in the skin cleaning supplies. use, grinding stripping of the stratum corneum of the epidermis outside, making the skin look even more whitening, such as a brand scrub.

16、 due to changes in the spending habits of the early and mid 1990s selling scrub or scrub cleanser cosmetics is now hard to find their trace. Biochemical methods: add an acidic compound used in skin care products by the erosion of the stratum corneum of the epidermis outside, so that it makes the ski

17、n look even more whitening accelerate the shedding speed, as a brand Facial Scrub .90 Early occurred the one thousand cases of skin damage events and their related complaints resulting from the use of such cosmetics, chemical peel cosmetics gradually withdraw from the market. Fade: keratinocytes to

18、stimulate melanin abatement so melanin desalination, commonly used functional ingredients of such products placenta extract bovine placental extract due to the impact of mad cow disease, the application of placenta extract by very The large limit be restricted in the late 1990s led to the developmen

19、t of such products in the market. 2 whitening products and its two typical the principle interference or blocking part of the formation of melanin. Century the development of science and technology has been the process of the formation of melanin has the latest understanding of know tyrosinase, dopa

20、chrome tautomeric, oxidase taken by inhibiting tyrosinase and other substances and endothelin referred to as “three enzymes a prime,” played an important role in the process of the skin melanin physiological reaction in their help, tyrosine step-by-step into the melanin annoying. generation and acti

21、vity, to interfere with or hinder the formation of melanin, or interfere with melanin biochemical reaction process, so that it reacts a certain intermediates, and there are many whitening skin care products can not be completed on the principles of market reaction melanin. “three enzymes prime “In f

22、act, the vast majority of modern mainstream skin lightening products all around to control the activity of this” three enzymes a prime, “expanded. substances that play an important role in the process allow darkening of the skin due to melanin production is normal skin physiological reaction if the

23、reaction is completely or partially blocked that is medically known as “albinism” skin part of the defense function deficit disorder. the common whitening products is to interfere with or block the part of the formation of melanin. interference or resistance skin melanin production during off harmfu

24、l substances produce intermediates such as dopa, dopa quinone, etc. 7,8. So because of individual differences, some people use this principle whitening products, skin damage occurs while a small number of continuing users also accelerated skin aging due to harmful substances in the skin increased oc

25、currence of white skin and not the United States, as dead like a pale face. Therefore, many whitening products is not recommended consumers continue to use, because they contain a factor that is not conducive to the health of the skin. The biggest lure weakened melanin production: by blocking ultrav

26、iolet rays from the sun, reducing ultraviolet radiation leads to excessive formation of melanin, many sunscreen whitening skin care products on the market. Hard to detect ultraviolet skin melanin produced one of the greatest incentive safe and effective sun protection products to take preventive mea

27、sures to reduce skin melanin hyperpigmentation widely accepted by Chinese consumers. Links to free papers Download Center the role of all the whitening material objects are targeted pigment mother cells and the secretion the melanin substances, whitening substance 9 present can be

28、 summarized as the four principle: (1 reduction - direct changes in melanin, melanin is secreted by the mother cell after the show called oxidized melanin oxidation state, it has a distinct black, but if the melanin to restore, becomes colorless reduced pigment Vitamin C is the use of this force 10.

29、 Vitamin C is one of the first skin experts identified as safety helps dilute melanin oral pharmaceutical but already formed spots, simply rely on oral achieve adequate blood concentration, in fact, there are difficulties. Vitamin C is the bodys natural anti-oxidant is the reducing agent. Reducing p

30、ower can dilute a variety of dyes, the mechanism of vitamin C melanin into colorless reduced melanin “will show a” black oxidized melanin, It is a two-way reflected when the concentration is low, it will reverse Replies become oxidized reproduce black, so terms of vitamin Blemish, unless long enough

31、 concentration to produce pigment reducing power, otherwise will soon reproduce the original color. Vitamin C is water-soluble, not easily absorbed through the skin, but also susceptible to oxidative deterioration, most of the vitamin C combined with the metal to maintain the stability of the Imam,

32、it was also their combination. (2 coagulation - tyrosine enzyme itself is a protein, the results of the enzyme protein coagulation, prompting enzyme loses the catalytic activity of many phenols, saccharides chemicals, have enzymes agglutination effects, such as is this principle of hydroquinone (hyd

33、roquinone 11,12. Visibility of hydroquinone after mercury compounds, commonly known as the HQ of hydroquinone crystals can be dissolved in 14 times as much water, soluble in alcohol and ether, it easily when in contact with air oxidation become brown, light environment under faster changing, so the

34、important save mode must try to seal and avoid light accelerated oxidation. HQ can be extracted from plants, and may be performed in organic synthesis, in the manufacture is not difficult, extracted directly from a plant having a physiological activity. bit hydroquinone effect is stronger for the se

35、lection of medicine. Phenol-based compounds of the protein coagulation, and the melanoma cells in the production of the black pigment particles are needed (tyrosinase, which itself is a kind of amino acid binding material of the copper ions, phenolic condensation tyrosine fermentation enzyme (Tyrosi

36、nase amino acid protein, make enzymes freeze to lose catalytic role of (Ctalysis and reduce the formation of melanin, so natural whitening Blemish effect. HQ made of cream, in accordance with the standards for drug cap of about 3-5% W / W, can cause systemic effects of skin absorption in excess of 5

37、%. As for the limits of medicated skin care products, at 2-3% limit. (3 Chimeric role - a major role in the tyrosinase copper ions, the many enzymes often have a metal ion as a coenzyme, such as acid, etc. integration role. Acid is a general term for several chemicals, most substances can be found i

38、n the natural fruit, such as: sugar cane, glycolic acid, malic acid in the apples, all belonging to the fruit termed “acid”. acid. Acid after reducing the adhesion between the cells of the skin, the stratum corneum, to speed up the cuticle cell loss and the melanin metabolism to achieve skin lighten

39、ing effect. Acid can remove the a rough excess of cuticle, the skin looks soft white, smooth, cuticle has a role to protect the skin, long-term use of acid may cause thinning of the skin becomes sensitive, so that the skin is fragile, lost confrontation ultraviolet function. (4 damaging effects - to

40、 destroy free radicals, resulting in changes in the structure of the melanosome and cell destruction caused by melanin. This method has some limitations in the application of this point also rarely applied in practice. All whitening products, regardless of how its mechanism, are to be achieved effec

41、tively inhibit melanin production, and the function of skin bleaching. Raising white class products and their typical schematic which is more advanced at this stage of the Dodge skin pigment principle, it is to promote melanoma cells by targeting nutrients the metabolism thereby shortening the cycle

42、 of melanocytes physiological, speed up the melanocytes horny and excreted. This is a new type of skin to raise white principle, it revolutionized mainstream the whitening principle to increase the carrier hyperpigmentation - Melanocytes, nutrition, metabolism of melanocytes to shorten the the physi

43、ological cycle melanocytes make melanin the cells faster horny discharge vitro effect to achieve a healthy raise white. Understand, this is the stage of the domestic “Dodge skin pigment cosmetics the latest products in the field of development of the prospect is very broad 13. In summary, reduce ski

44、n pigmentation make skin look younger, healthier consumers of the right to pursue but not to damage the health of the skin in exchange for a temporary white Do not make the mistake to pursue a pale face. Dodge skin pigment cosmetics gone through two stages, whitening products whitening class to “rai

45、se the white” concepts and product launches that the increase in which scientific and technological content, but also to ensure the effectiveness of whitening cosmetics and security. IV. Prospects for the development of skin lightening cosmetics with the affluent life and social contacts, we need to

46、 pay attention to the image of the individual, we need more self-confidence a good personal image various social challenges, but if the skin is unhealthy, just as their predecessors. With the rapid increase in Chinas rapid economic growth, the purchasing power of the population continued positive gr

47、owth said, “The skin does not exist MaoJiangYanFu?” the health of the skin are not, how can we talk about on the beautiful and nice, you can determine urbanization of the rural population, the increase of social interaction factors can be speculated that the Dodge skin pigment skin-care products, a huge market capacity, and will be long-term growth at a faster speed. References: 1 Zhang Fuqiang Chinese cosmetics industrys status quo and future J. The Daily Chemical Sciences, 2001,24 (2):