消化道常见肿瘤化疗方案

1、1.胃癌FLP :DDP50mg/m22hd1,15CF2200mg/ m2hd1,8,155-FU22000mg/m22hd1,8,15q28d+ Cape/Oxa:capecitab ineOxaor Oxa:21000mg/m , bid pod1-14270mg/m d1,82130mg/m d1q22d*6cyclesq22d*6cycles+ FUFOX:Oxaliplatin250mg/m2hd1,8,15,22CF200mg/m22hd1,8,15,225-FU22000mg/m22hd1,8,15,22 every 6 weeks*6 cycles+ 5-FU+Iri no

2、teca n2Irinotecan 80mg/m1.5h2h22hd1,8,15,22d1,8,15,22CF5-FU200mg/m22000mg/md1,8,15,22q6w+ Cape+ Irino teca nIrino teca n80mg/m21.5hd1,8cape22000mg/m /d, pod1-14.q22d2+ Docetaxel + DDPDceetaxel 35mg/md1,8DDP40mg/m+ 5-FU + Oxa +Docetaxel5-FU21500mg/m22hd1,8Oxa70mg/m22hd1,8Docetaxel35mg/m22hd1,8 q22d2d

3、1,8 .q22d+ Cape + Oxaliplati n + Docetaxel Cape1600mg/m2/dd1-14Oxa70mg/m2d1,8Docetaxel235mg/md1,8 - q22d2. 结肠癌化疗方案（推荐）Adjuvant Chemotherapy or Chemotherapy for Advanced or Metastatic Disease2+ FCF:CF 200mg/m 2h25-FU 500mg/m 1hweekly*62+ Capecitab in e:Capecitabi ne 1250mg/m bid d1-14 every3wks*24wks

4、2+ FOLFOX4:CF 200mg/m 2h2 25-FU 400mg/m bolus then 600mg/m 22h d1-2, every 14days*12 cycles2Oxaliplatin 85mg/m 2h d1Chemotherapy for Advanced or Metastatic DiseaseFOLFIRI:Irino teca nCF5-FU180mg/m2200mg/m22400mg/m bolus2h d12h2,then 600mg/m 22h d1-2 every 14days*12 cyclesIFL:Irino teca n125mg/m21.5h

5、d1,8,15,22CF20mg/m22hd1,8,15,225-FU500mg/m21hd1,8,15,22repeat every 6 wks.Irino teca n:Irino teca n2125mg/m1.5hd1,8,15,22repeat every 6 wks.2Protracted IV 5-U:5-FU300mg/m /d CIV+ Bevacizumab + 5-FU containing regime ns:Bevacizumab 5mg/kg iv every 2 wksFCFFOLFOX4 FOLFIRI IFL2 2+ Cetuximab+ Irinotecan

6、: Cetuximab 400mg/m 1st infusion,then 250mg/m weekly2Irinotecan 125mg/m 1.5hd1,8,15,22 repeat every 6 wks.3. 直肠癌化疗方案Adjuvant Chemotherapy for patients receiving proeoperative RCT:25-FU 500mg/m 1h2CF 200mg/m 2h once a week for 6 weeks*3 cyclesAdjuvant Chemradiotherapy for patients not receiving proeo

7、perative RCT:25-FU 500mg/m 1h2CF 200mg/m 2h once a week for 6 weeks*1 cycles the n receive RCT and the n 2cycles more.Aduvant Chemotherapy for patients not receiving proeoperative RCT:FOLFOX4Dosing schedules for concurrent RCT:2RT+5-FU civ: 5-FU225mg/ over24h 7d/wk during RT2 2RT+FCF: 5-FU 400mg/m +

8、CF 20mg/m for 4d during wk 1 and 5 of RTChemotherapy for Advanced or Metastatic DiseaseFCF:CF 200mg/m2 2h25-FU 500mg/m 1h weekly*6Capecitab in e: Cap ecitab ine 1250mg/m2 bid d1-14 every3wks*24wks2FOLFOX4:CF200mg/m 2hd12 25-FU 400mg/m bolus then 600mg/m 22h d1-2 every 14days*12 cycles2Oxaliplatin 85

9、mg/m 2hd12FOLFIRI:Irino teca n180mg/m 2h d12CF200mg/m 2h2 25-FU 400mg/m bolus then 600mg/m 22h d1-2 every 14days*12 cycles2IFL:Irino teca n125mg/m1.5hd1,8,15,22CF20mg/m 22hd1,8,15,225-FU2500mg/m1hd1,8,15,22 repeat every 6 wksIrino teca n:125mg/m1.5h d1,8,15,22repeat every 6 wks2Protracted IV 5-U: 30

10、0mg/m /d CIVBevacizumab + 5-FU containing regime ns: Bevacizumab 5mg/kg iv every 2 wksFCFFOLFOX4 FOLFIRI IFL2 2Cetuximab+ Irino teca n:Cetuximab 400mg/m 1st in fusi on ,the n 250mg/m weekly2notecan 125mg/m 1.5h d1,8,15,22 repeat every 6 wks.4. 结直肠癌化疗方案FCF （年龄70岁）2CF 500mg/m5-FU 500mg/md1,8,15,22,29,

11、36 2h2d1,8,15,22,29,36 1hCape/Oxa:capecitab ine21000mg/mbid po d1-14Oxa:70mg/m2d1,8FUFOX :Oxa:50mg/m2d1,8,15,222hCF2500mg/md1,8,15,222h5-FU22000mg/md1,8,15,2222hIrino teca n/CapeIrino teca n80mg/m2d1,81.5hCapecitab ine21000mg/mbid pod1-14FCF/Iri noteca nIrino teca n80mg/m2d1,8,15,221.5hCF2500mg/md1,8,15,222h5-FU22000mg/md1,8,15,2224h civFUFOX/ Cetuximab5. 食管癌非手术方案（推荐）同步放化疗：RT 50-50.4GY + 5-FU/DDP 美国RT 40GY + 5-FU/DDP St.Georg化疗方案（Dr.Mantovani in St.Georg）:FLP （同胃癌）FUFOX （同胃癌）Docetaxel/DDP :2DXL 35mg/md1,82DDP 40mg/md1,8.q28dVi no relbi ne/DDP :2VNB 25mg/