多肽修饰介孔二氧化硅

1、Advances in Peptide Functionalization on Mesoporous Silica Nanoparticles for Controlled Drug ReleaseJing-Jing Hu , Dong Xiao , and Xian-Zheng Zhang *DOI: 10.1002/smll.201600325DOI: 10.1002/smll.201600325From the ContentsIn troductionTarting Peptides. Stimuli-responsive Peptides. Multifunctional Chei

2、ric tidesxt. Conclution. DOI: 10.1002/smll.2016003251. IntroductionDOI: 10.1002/smll.2016003251. IntroductionPeptidesproteinCarcinoma or targeting RGDvmany carciomaP-13interleukin-13(白介素-13)glioma head and neck cncer etc.T22 PeptideCXCR4（趋化因子受体）Lymphoma cellsSPP4hapatocellular carcinomaTAT Peptidesn

3、uclear pore complexsKLA mitochondriatLyp.I peptideNRP(Neuropjlin)breast cancers glioma cells,endothelial cells of angiogenic blood vesselsDOI: 10.1002/smll.2016003252. Targeting Peptides2.1. Tumor Cell Membrane Targeting PeptidesMater. Chem. B 2015 , 3 , 39DOI: 10.1002/smll.2016003252. Targeting Pep

4、tides2.1. Tumor Cell Membrane Targeting PeptidesJ. Mater. Chem., 2012, 22, 14608J. Am. Chem. Soc. 2013, 135, 47994804DOI: 10.1002/smll.2016003252. Targeting Peptides2.1. Tumor Cell Membrane Targeting PeptidesAdv. Funct. Mater. 2015, 25, 687695DOI: 10.1002/smll.2016003252. Targeting Peptides2.1. Tumo

5、r Cell Membrane Targeting PeptidesNat. Mater. 2011 , 10 , 389ACS Nano 2012 , 6 , 2174DOI: 10.1002/smll.2016003252. Targeting Peptides2.2 . Nuclear Location SignalJ. Am. Chem. Soc. 2012, 134, 57225725DOI: 10.1002/smll.2016003252. Targeting Peptides2.2 . Nuclear Location SignalAdv. Funct. Mater. 2015,

6、 25, 29612971Int. J. Nanomed. 2015, 10, 1855.3. Stimuli-Responsive Peptides3.1. Enzyme-Responsive PeptidesNano Res. 2015, 8(6): 189319053.2 . pH-Responsive Peptides3. Stimuli-Responsive PeptidesAngew. Chem. Int. Ed. 2013, 52, 7487 7491Chem. Commun., 2014, 50, 3184-3186 |3.3. Temperature-Responsive Peptides3. Stimuli-Responsive PeptidesChem. Commun., 2013, 49, 9932-9934Temperature-controlled release by changes in the secondary structure of peptides anchored o