药用植物资源

1、会计学1药用植物资源药用植物资源NOCH3OCH3OOOH-+A GluHOOHOOOOOCH3gluH3COH3COOHOOHOOHOHOHOHOOHCOOHOHOH绿原酸HOOCOHOH咖啡酸OOOHOOHOHglu木犀草素木犀草苷菘蓝菘蓝马蓝马蓝OHOOHOHOOOCH2OHOHOCH3NNO苦 参NNOO苦参碱氧化苦参碱NNONNOONNOHONONCH3NONOHNONNNO苦参碱氧化苦参碱羟基苦参碱去氢苦参碱N-甲基金雀花碱巴普叶碱安那吉碱OHOHOHHOHHOHOHCNOH垂盆草苷OOH3COH3COOOHOHOOHH3COOOH3COH3CO滨蒿内酯茵陈色原酮OHOHHO11H

2、OOH己烯雌酚OHOHHO11OHOHHO11OOOHOHR1R2大黄酚大黄酚 R1 = CH3, R2 = H大黄素大黄素 R1 = CH3, R2 = OH 大黄素大黄素-6-甲醚甲醚 R1 = CH3, R2 = OCH3 SCOO-NH3+OSHOCOO-O+NH4+SHO-H2OSSO蒜酶蒜氨酸大蒜素OOOHR1R2R3HOHOOOOR1R2R3银杏内酯A银杏内酯B银杏内酯C银杏内酯M银杏内酯JOHOHOHHOHHOHOHOHHHHOHOHOHOOMeR1OHOOR2HOOHO R1 R27-去甲基双黄酮 OH OH白果双黄酮 OCH3 OH异银杏双黄酮 OH OCH3OHCOOH(

3、CH2)7CH=CH(CH2)5CH3OHCOOH(CH2)14CH3OHCOOH(CH2)13CH3OH(CH2)7CH=CH(CH2)5CH3白果酸白果酚氢化白果酸氢化白果亚酸OOOH3CCH3丹参酮AOH冰片（龙脑）OOOH3CCH3丹参酮AHOOC C NHOCH2CHNH2COOHNNCHOHCHCOOHOCH3川芎嗪阿魏酸OCHCH2CH2CH3O藁本内酯NNOCHCH2CH2CH3OCHOHCHCOOHOCH3阿魏酸藁本内酯OR1OOHOHOR2 R1 R2 xyl(2,3,4-三OAc） glu 乙酰黄芪苷xyl(2,3,-二OAc） glu 黄芪苷xyl(2,4-二OAc)

4、glu 异黄芪苷xyl(2-OAc) glu 黄芪苷xyl glu 黄芪苷xyl-2-glu H 黄芪苷OOHOOOHOOHOHCH2OHOOHOOCH2OHOOHOHOHCH2OHOOHOHOHMeSaponin DP-1OOHOOOHOOHOHCH2OHOOOOHCH2OHOOHOHOHMeSaponin DP-2OOHOHOHMeOOHOOOHOOHOHCH2OHOOHOOHCH2OHOOHOHOHMeSaponin DP-3OOOOHOOCH2OHOOHOHOHCH2OHOOHOHOHMeSaponin DP-4OOOOOOOHCH2OHOOHOHOHMeOOHOHOHMeSaponi

5、n DP-5OOOOOHOOHCH2OHOOHOHOHMeSaponin DP-6OOOOOOHOHCH2OHOOHOHOHMeSaponin DP-7OOOOOHOHOHCH2OHSaponin DP-8OOOOHOOOOOOOOHOH2CHOOHOHCH3OCOCH3CH3OHCH3OHR1R2洋地黄毒苷元 R1R2H羟基洋地黄毒苷元 R1H，R2=OH异羟基洋地黄毒苷元 R1=OH,R2=H双羟基洋地黄毒苷元 R1=R2=OH吉他洛苷元 R1=H,R2=-OOCH洋地黄毒苷 R1R2H(狄吉妥辛)羟基洋地黄毒苷 R1H，R2=OH异羟基洋地黄毒苷 R1=OH,R2=H(地高辛)双羟基洋地

6、黄毒苷 R1=R2=OH吉他洛苷 R1=H,R2=-OOCH毛花洋地黄苷A、B、C、D、E西地蓝(去乙酰毛花洋地黄苷C)毛花洋地黄叶粉发酵(28-31，8-10h)70%乙醇提取，浓缩，除叶绿素等杂质滤液氯仿萃取，5NaOH洗涤除有色杂质，水洗至中性，Na2SO4干燥，浓缩氯仿提取物丙酮提取，低温放置晶体（洋地黄毒苷粗品）活性碳脱色，丙酮多次重结晶洋地黄毒苷成品COOR5OR3OR1R2R413591311710141817192021222627282930COOHR1R2R3R4R4R5R1R2R3COOR5R1R4OR3R2OR1R3OR2OOCH3OHOOCH3OCH3OOCH3OHO

7、CH3OOOCH3OCH3H3COHHOgluOCOH2COCH3COOHHOgluCOOCH3HOH2COHHOgluOHCOOHOH2CCH3COOHHOgluCOOHHOH2CHOOHHOgluCOOHHOH2CHOOHHOgluOCOOCH3HOH2CCCH3COHHCOOHHOgluOCOOCH3HOH2CCCH3COHCOHOHHOgluOCOOCH3HOH2CCCHOHHCOOHHOgluOCOOCH3HOH2CCCHOHCOHHOCOOHOHHOgluOCOOCH3HOH2CCCHOHHCOH3COOHHOgluOCOOCH3HOH2CCCHOHCOHH3COHOCOOH熊果酸

8、齐墩果酸NNOOH3CH2COHONNOOH3CH2COHOONNOCH2CH3NNOOH3CH2COHOHONNOOH3CH2COHOHOCH2N依立替康拓扑替康10-羟基喜树碱HCHC C O123468911NHCOHOOHH3CCOOOHOOCOHOCOCH3OHOHHHOOCH3(H3C)2HCOOCH(CH3)2莪术醇莪二酮OHHOHOHOOHOOHHOHOHOOO冬凌草甲素冬凌草乙素glcHOOHglcOR1OR2OOO R1 R2H =O OH OH H OHNMeOMeOHOMeO青藤碱OOH2COCOOOHOH2CHOHOOHHOH芍药苷OHOOHOOHOHOHOHOOHCOOHOHOH绿原酸