白血病免疫分型ppt课件

1、1l 血液免疫科 葛繁梅 提高恶性血液病诊断与分型的准确性提高恶性血液病诊断与分型的准确性,检测残留病灶，判断预后检测残留病灶，判断预后v 区分淋巴细胞与髓性，区分淋巴细胞与髓性， 区分区分T细胞与细胞与B细胞细胞v 确定白血病细胞的阶段确定白血病细胞的阶段v 覆盖率高于基因及染色体，尤其对淋巴系统覆盖率高于基因及染色体，尤其对淋巴系统v 敏感性高于形态及染色体敏感性高于形态及染色体v 比染色体及基因分析快捷，但特异性比之差比染色体及基因分析快捷，但特异性比之差v 解释结果的医师要有丰富的知识解释结果的医师要有丰富的知识v 对对M4、M5、M6、M7的鉴别不太敏感的鉴别不太敏感2;.34567

2、891011121314l五、白血病具 体类型分析15R2R3R416File: wangqingming.007Acquisition Date: 22-Nov-04Region% GatedR1100.00R20.99R394.63R40.25R2R3R4灧灧瑎瑎 17File: baixiurong.001Acquisition Date: 22-Apr-05Region% GatedR1100.00R232.40R324.90R423.91R513.59R6 1.86R2R3R4R5R618File: wangxing.001Acquisition Date: 05-Jan-05Reg

3、ion% GatedR1100.00R2 8.91R376.38R4 1.06R512.67R2R3R4R519R2R3R4R5R620File: wangyushu.001Acquisition Date: 13-Dec-04Region% GatedR1100.00R214.67R310.11R417.55R536.03R64.20R73.24R2R3R4R5R6R7灧灧瑎瑎 撓崳浪湹碧栒 R3 26.55%,碧 CD34,CD117,HLA-DR,CD38,CD33dim婙彌湊佫碧CD64,CD13,寵撓崳浪湹敵鲄湊佫埃R 捄 36.88%,碧 CD64,CD38,HLA-DR,CD14

4、,CD33,CD13寵泊崊犗禃澙湊佫埃R7 8.1%,SSC灉（碧CD33,CD13寵牷婪枒。湊佫埃罕枒浪湹湊佫伋棛姲M4E0鴧儖枒埃21File: huguangqing.001Acquisition Date: 16-Jun-05Region% GatedR1100.00R2 4.08R365.72R417.70R5 5.36R6 3.47R2R3R4R5R622File: fangchanghua.004Acquisition Date: 08-Nov-05Gate: G1Region% GatedX MeanY MeanR1100.0074.5593.45R29.9243.53621.

5、59R370.0845.896.55R47.2055.5969.99R53.20236.75268.43R65.49329.4183.33R2R3R4R5R623File: chenjianhui.001Acquisition Date: 17-Feb-05Region% GatedR1100.00R217.81R328.50R436.75R5 3.08R6 7.66R2R3R4R5R624File: baiyanyu.001Acquisition Date: 03-Mar-05Region% GatedR1100.00R2 7.02R375.60R411.13R2R3R425File: su

6、nhongwei.001Acquisition Date: 08-Dec-05Gate: G1Region% GatedX MeanY MeanR1100.00130.88118.47R26.5368.18492.38R378.1486.4088.92R49.64376.6090.53R51.67208.22393.93R2R3R4R5撓崳 湹碧栒埃 R3 78.14%,碧CD34,CD22,CD19,CD10,cCD79a,CD20（ 婙忳湊佫碧CD13. 姫碧CD33,CD117,cCD3,MPO,“B 湊佫（鬟嶗罕枒B 湊佫伋棛姲ALL-B）捲帨埃B-ALL26File: gaoyanl

7、ai.001Acquisition Date: 15-Jul-05Gate: G1Region% GatedX MeanR1100.00378.54R2 3.90 74.38R326.93 71.22R464.34532.80R5 1.82 254.28R6 1.52 57.10R7 9.41 78.04R8 1.64 59.98R2R3R4R5R627File: yangxingxin.003Acquisition Date: 23-Nov-05Gate: G1Region% GatedX MeanY MeanR1100.0035.17297.72R242.3831.17324.59R346.5432.76151.63R48.6752.23893.72R2R3R4撓崳 湹碧栒埃 R3 46.54%（碧CD34,cCD3,CD5,CD7,TdT,恍碧CD3,姫碧CD4,CD8,CD117,CD13,CD22,MPO,cCD79a,CD19,CD16,CD56,CD25,CD2,敵鲄 T 湊佫埃R2 42.38%（碧cCD3,CD25,CD5