辅酶一NAD与老年化疾病

1、精选课件1Age-related diseases and cancer COENZYME ICOENZYME I精选课件2精选课件3精选课件4Eric Verdin. (2015). Special Section 350（6265）: 1208-1213.NAD biosynthetic pathways and metabolism in different cellular compartments.精选课件5精选课件6E F. Fang,. (2017). NAD+: a key metabolic regulator with great therapeutic potential

2、: 1120-1143.NAD availability can influence the activity of three groups of master regulator enzymesthe sirtuins, the PARPs and cyclic ADP-ribose synthases. Each group of enzymes regulate many biological processes and can thus couple changes in NAD levels with a wide range of physiological responses.

3、精选课件7精选课件81980s1980s1930s1930sAge-related diseases and cancer could be the consequence of a decline in NAD+ concentrationsAmanda Garrido (2017). Trend in cancer 181: 181-199.Metabolic syndrome including cardiovascular disorders, type 2 diabetes and obesity, Neurodegenerative diseases such as Alzheim

4、er and Parkinsondiseases, arthritis, and osteoporosis, and cancer are some of the diseases that commonly affect human health during aging.精选课件9精选课件10GSultani. (2017). Trends in Molecular Medicine23（10）: 900-918精选课件11GSultani. (2017). Trends in Molecular Medicine23（10）: 900-918精选课件12GSultani. (2017). Trends in Molecular Medicine23（10）: 900-918精选课件13精选课件14GSultani. (2017). Trends in Molecular Medicine23（10）: 900-918精选课件15GSultani. (2017). Trends in Molecular Medicine23（10）: 900-918精选课件16GSultani. (2017). Trends in Molecular Medicine23（10）: 900-918精选课件17GSultani. (2017). Trends in Mole