海藻乙醇提取物抗菌活性的研究

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6、ar， 42： 165173 STUDY ON THE ANTIBACTERIAL ACTIVITIES OF THE ETHANOL EXTRACTS OF SEAWEED （ C. K. Tseng） XU Nian-jun， FAN Xiao， HAN Li-jun， LIN Wei， ZENG Cheng-Kui （ Institute of Oceanology ， The Chinese Academy of Sciences ， Oingdao ， 266071） Abstract The ethanoi extracts of seaweed beionging to Chio

7、rophyta， Rhodophyta and Phaeophyta， coiiected from Shandong coast in May 2000， were assayed their activities against two kinds of bacteria of Escherichia coli and Staphylococcus aurens . As a resuit， the water phase of extracts of Symphyocladia latiuscula ， Desmarestia uiridis ， Rhodomela conferuoid

8、es and Ulua pertusa showed activities against Escherichia coli . The Et0Ac phase of extracts of Symphyocladia latiusSargassum kjelimanianum， Rhodomela conferuoides ， Leathesia difformes and the water phase of extract of Desmarestia cula ， uiridis showed activities against Staphylococcus aurens . Bro

9、wn aigae had the highest activities， then red aigae， and green aigae had the iowest activities. Five species of seaweed， Desmarestia uiridis ， Sargassum kjelimanianum， Leathesia difformes ， Symphyocladia latiuscula and Rhodomela conferuoides showed high antibacteriai activities. Thin iayer chromatog

10、ra（ TLC） phy was used to separate the extracts of the five species of seaweed and each band was examined for their anti-bacteriai activities. It turned out that 16 bands showed activities against Staphylococcus aurens and 11 bands showed activities against Escherichia coli . Three bands from Desmarestia uiridis and Sargassum kjelimanianum had powerfui activities against Staphyiococcus aurens and two bands from Desmarestia uiridis couid inhibit the growth of Escherichia coli vigoriy. Compared with some common antibiotics， the acti