SRT3190 _CXCR Antagonist - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemESRT3190Cat. No.: HY-13021CAS No.: 1204707-73-2分式: CHFNOS分量: 475.53作靶点: CXCR作通路: GPCR/G Protein; Immunology/Inflammation储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 DMSO : 100 mg/mL (210.29 mM)*

2、 means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 2.1029 mL 10.5146 mL 21.0292 mL5 mM 0.4206 mL 2.1029 mL 4.2058 mL10 mM 0.2103 mL 1.0515 mL 2.1029 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。体内实验请根据您的实验动物和给药式选择适当的溶解案，配制前请先配制澄清的储备液，再依次添加助溶剂(为保证实验结果的可靠性，体内实验的

3、作液，建议您现现配，当天使；澄清的储备液可以根据储存条件，适当保存；以下溶剂前的百分 指该溶剂在您配制终溶液中的体积占)：1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.5 mg/mL (5.26 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.5 mg/mL (5.26 mM); Clear solution3. 请依序添加每种溶剂： 10% DMSO 90% corn oil1/2 M

4、aster of Small Molecules 您边的抑制剂师www.MedChemESolubility: 2.5 mg/mL (5.26 mM); Clear solutionBIOLOGICAL ACTIVITY物活性 SRT3190种 CXCR2 的拮抗剂，可于趋化因介导的疾病研究。IC50 & Target CXCR2体外研究 SRT3190 (Reference Example 2) is an antagonist of CXCR2, used in the research of chemokine mediateddiseases 1.REFERENCES1. Premji Meghani, et al. Pyrimidyl sulfonaminde derivative and its use for the treatment of chemokine mediated diseases.WO2010007427A1McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;/p>