Efonidipine-hydrochloride-NZ-105-hydrochloride-DataSheet-生命科学试剂-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEEfonidipine hydrochlorideCat. No.: HY-12502BCAS No.: 111011-53-1Synonyms: NZ-105 hydrochloride分式: CHClNOP分量: 668.12作靶点: Calcium Channel作通路: Membrane Transporter/Ion Channel; Neuronal Signaling储存式: Please store the product under

2、the recommended conditions inthe COA.溶解性数据体外实验 DMSO : 8.5 mg/mL (12.72 mM; Need ultrasonic and warming)Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 1.4967 mL 7.4837 mL 14.9674 mL5 mM 0.2993 mL 1.4967 mL 2.9935 mL10 mM 0.1497 mL 0.7484 mL 1.4967 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。BIO

3、LOGICAL ACTIVITY物活性 Efonidipine(NZ-105)盐酸盐T型和L型钙离通道双重 阻断剂。REFERENCES1. Ikeda K, et al. Efonidipine, a Ca(2+)-channel blocker, enhances the production of dehydroepiandrosterone sulfate in NCI-H295R humanadrenocortical carcinoma cells. Tohoku J Exp Med. 2011;224(4):263-71.2. Nakano N, et al. Effects o

4、f efonidipine, an L- and T-type calcium channel blocker, on the renin-angiotensin-aldosterone system inchronic hemodialysis patients. Int Heart J. 2010 May;51(3):188-92.1/2 Master of Small Molecules 您边的抑制剂师www.MedChemE3. Suzuki S, et al. Beneficial effects of the dual L- and T-type Ca2+ channel bloc

5、ker efonidipine on cardiomyopathic hamsters. Circ J. 2007Dec;71(12):1970-6.4. Lee TS, et al. Actions of mibefradil, efonidipine and nifedipine block of recombinant T- and L-type Ca channels with distinct inhibitorymechanisms. Pharmacology. 2006;78(1):11-20.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792; 021-5