Betahistine-dihydrochloride - Histamine Receptor 抑制剂 - 生命科学试剂 - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEBetahistine dihydrochlorideCat. No.: HY-B0524ACAS No.: 5579-84-0分式: CHClN分量: 209.12作靶点: Histamine Receptor作通路: GPCR/G Protein; Immunology/Inflammation; NeuronalSignaling储存式: 4C, protect from light, stored under nitrogen* In solv

2、ent : -80C, 6 months; -20C, 1 month (protect fromlight, stored under nitrogen)溶解性数据体外实验 H2O : 50 mg/mL (239.10 mM)DMSO : 33.33 mg/mL (159.38 mM; Need ultrasonic)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 4.7819 mL 23.9097 mL 47.8194 mL5 mM 0.9564 mL 4.

3、7819 mL 9.5639 mL10 mM 0.4782 mL 2.3910 mL 4.7819 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。BIOLOGICAL ACTIVITY物活性 Betahistine 双盐酸盐是组胺H3受体抑制剂。REFERENCES1. Lacour, M. and O. Sterkers, Histamine and betahistine in the treatment of vertigo: elucidation of mechanisms of action. CNS Drugs,1/2 Master

4、of Small Molecules 您边的抑制剂师www.MedChemE2001. 15(11): p. 853-70.2. Gbahou, F., et al., Effects of betahistine at histamine H3 receptors: mixed inverse agonism/agonism in vitro and partial inverse agonismin vivo. J Pharmacol Exp Ther, 2010. 334(3): p. 945-54.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fax: 02