Pimecrolimus-SDZ-ASM-981-DataSheet-生命科学试剂-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEPimecrolimusCat. No.: HY-13723CAS No.: 137071-32-0Synonyms: SDZ-ASM 981分式: CHClNO分量: 810.45作靶点: Others作通路: Others储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 DMSO : 32 mg/mL (39.48 mM)* means s

2、oluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 1.2339 mL 6.1694 mL 12.3388 mL5 mM 0.2468 mL 1.2339 mL 2.4678 mL10 mM 0.1234 mL 0.6169 mL 1.2339 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。BIOLOGICAL ACTIVITY物活性 Pimecrolimus是免疫亲和素（immunophilin）配体，能特异地与胞质受体（immunop

3、hilin macrophilin-12）相结合。户使本产品发表的科研献1/2 Master of Small Molecules 您边的抑制剂师www.MedChemE J Cell Sci. 2019 Apr 26. pii: jcs.227777.See more customer validations on HYPERLINK / www.MedChemEREFERENCES1. Nghiem, P., G. Pearson, and R.G. Langley, Tacrolimus and pimecrolimus: from clever prokaryotes to inhib

4、iting calcineurin and treatingatopic dermatitis. J Am Acad Dermatol, 2002. 46(2): p. 228-41.2. Gupta, A.K. and M. Chow, Pimecrolimus: a review. J Eur Acad Dermatol Venereol, 2003. 17(5): p. 493-503.3. Stuetz, A., M. Grassberger, and J.G. Meingassner, Pimecrolimus (Elidel, SDZ ASM 981)-preclinical pharmacologic profile and skinselectivity. Semin Cutan Med Surg, 2001. 20(4): p. 233-41.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;F