Gatifloxacin-BMS-206584-01-DataSheet-生命科学试剂-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEGatifloxacinCat. No.: HY-10581CAS No.: 112811-59-3Synonyms: BMS 206584-01; PD 135432; AM-1155分式: CHFNO分量: 375.39作靶点: Bacterial作通路: Anti-infection储存式: 4C, stored under nitrogen* In solvent : -80C, 6 months; -20C, 1 month (stored

2、undernitrogen)溶解性数据体外实验 H2O : 1 mg/mL (2.66 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 2.6639 mL 13.3195 mL 26.6390 mL5 mM - - -10 mM - - -请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。BIOLOGICAL ACTIVITY物活性 Gatifloxacin第四代氟喹诺酮类抗素，能抑制细菌的DNA旋转酶和拓扑异构酶IV。户使本产品发表的科研献 Patent. US

3、20180263995A1.See more customer validations on HYPERLINK / www.MedChemE1/2 Master of Small Molecules 您边的抑制剂师www.MedChemEREFERENCES1. Fukuda, H., S. Hori, and K. Hiramatsu, Antibacterial activity of gatifloxacin (AM-1155, CG5501, BMS-206584), a newly developedfluoroquinolone, against sequentially acq

4、uired quinolone-resistant mutants and the norA transformant of Staphylococcus aureus. AntimicrobAgents Chemother, 1998. 42(8): p. 1917-22.2. Jensen, H., et al., Comparison of ophthalmic gatifloxacin 0.3% and ciprofloxacin 0.3% in healing of corneal ulcers associated withPseudomonas aeruginosa-induce

5、d ulcerative keratitis in rabbits. J Ocul Pharmacol Ther, 2005. 21(1): p. 36-43.3. Cheung, O., et al., Gatifloxacin-induced hepatotoxicity and acute pancreatitis. Ann Intern Med, 2004. 140(1): p. 73-4.4. Fteha, A., et al., Gatifloxacin induced torsades de pointes. Pacing Clin Electrophysiol, 2004. 27(10): p. 1449-50.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792; 02