Sinensetin-Pedalitin-permethyl-ether-DataSheet-生命科学试剂-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemESinensetinCat. No.: HY-N0297CAS No.: 2306-27-6Synonyms: Pedalitin permethyl ether分式: CHO分量: 372.37作靶点: PGE synthase; TNF Receptor作通路: Immunology/Inflammation; Apoptosis储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-2

2、0C 1 month溶解性数据体外实验 DMSO : 12.5 mg/mL (33.57 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 2.6855 mL 13.4275 mL 26.8550 mL5 mM 0.5371 mL 2.6855 mL 5.3710 mL10 mM 0.2686 mL 1.3428 mL 2.6855 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。体内实验请根据您的实验动物和给药式选择适当的溶解案，配制前请先配制澄的储备液，再

3、依次添加助溶剂(为保证实验结果的可靠性，体内实验的作液，建议您现现配，当天使；澄的储备液可以根据储存条件，适当保存；以下溶剂前的百分 指该溶剂在您配制终溶液中的体积占)：1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 1.25 mg/mL (3.36 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 1.25 mg/mL (3.36 mM); Clear solution3. 请依序添加每种溶剂：

4、10% DMSO 90% corn oil1/2 Master of Small Molecules 您边的抑制剂师www.MedChemESolubility: 1.25 mg/mL (3.36 mM); Clear solutionBIOLOGICAL ACTIVITY物活性 Sinensetin个能够在果中发现的甲 化 酮，有很强的抗管和抗炎症的能。REFERENCES1. Kang SI et al. Sinensetin enhances adipogenesis and lipolysis by increasing cyclic adenosine monophosphate l

5、evels in 3T3-L1adipocytes. Biol Pharm Bull. 2015;38(4):552-8.2. Shin HS et al. Sinensetin attenuates LPS-induced inflammation by regulating the protein level of IB-.Biosci Biotechnol Biochem.2012;76(4):847-9.3. Lam IK et al. In vitro and in vivo structure and activity relationship analysis of polymethoxylated flavonoids: identifying sinensetin as anovel antiangiogenesis agent. Mol Nutr Food Res. 2012 Jun;56(6):945-56.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-379