GlyRS-IN-1 - GlyRS 抑制剂 - 生命科学试剂 - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEGlyRS-IN-1Cat. No.: HY-108940CAS No.: 112921-11-6分式: CHNOS分量: 403.37作靶点: Bacterial; Aminoacyl-tRNA Synthetase作通路: Anti-infection; Metabolic Enzyme/Protease储存式: -20C, stored under nitrogen* In solvent : -80C, 6 months; -20C, 1 mo

2、nth (stored undernitrogen)溶解性数据体外实验 DMSO : 100 mg/mL (247.91 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 2.4791 mL 12.3956 mL 24.7911 mL5 mM 0.4958 mL 2.4791 mL 4.9582 mL10 mM 0.2479 mL 1.2396 mL 2.4791 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。体内实验 请根据您的实验动物和给药式选择适当的溶

3、解案，配制前请先配制澄清的储备液，再依次添加助溶剂(为保证实验结果的可靠性，体内实验的作液，建议您现现配，当天使；澄清的储备液可以根据储存条件，适当保存；以下溶剂前的百分 指该溶剂在您配制终溶液中的体积占)：1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 1.67 mg/mL (4.14 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 1.67 mg/mL (4.14 mM); Clear sol

4、ution3. 请依序添加每种溶剂： 10% DMSO 90% corn oilSolubility: 1.67 mg/mL (4.14 mM); Clear solution1/2 Master of Small Molecules 您边的抑制剂师www.MedChemEBIOLOGICAL ACTIVITY物活性 GlyRS-IN-1氨酰 tRNA 合酶 (GlyRS) 的抑制剂来专利 WO 2017066459 A1。GlyRS-IN-1 也可以抑制细菌的长。IC50 & Target GlyRS 1, Bacterial 1REFERENCES1. Xiang-Lei Yang, et al. INHIBITION OF NEDDYLATION USING GLYCYL-tRNA SYNTHETASE INHIBITORS. WO 2017066459 A1.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;