Firategrast-SB-683699-DataSheet-生命科学试剂-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEFirategrastCat. No.: HY-14951CAS No.: 402567-16-2Synonyms: SB 683699分式: CHFNO分量: 499.5作靶点: Integrin作通路: Cytoskeleton储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 DMSO : 100 mg/mL (200.20 mM)Etha

2、nol : 50 mg/mL (100.10 mM)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 2.0020 mL 10.0100 mL 20.0200 mL5 mM 0.4004 mL 2.0020 mL 4.0040 mL10 mM 0.2002 mL 1.0010 mL 2.0020 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。体内实验 请根据您的实验动物和给药式选择适当的溶解案，配制前请先配制澄清的储备

3、液，再依次添加助溶剂(为保证实验结果的可靠性，体内实验的作液，建议您现现配，当天使；澄清的储备液可以根据储存条件，适当保存；以下溶剂前的百分 指该溶剂在您配制终溶液中的体积占)：1. 请依序添加每种溶剂： 1% SBE-beta-CDSolubility: 0.2 mg/mL (0.40 mM); Clear solution; Need ultrasonic and warming1/2 Master of Small Molecules 您边的抑制剂师www.MedChemEBIOLOGICAL ACTIVITY物活性 Firategrast种服 41/47 整合素拮抗剂。IC50 & T

4、arget 41/47 1体外研究 Firategrast is an orally bioavailable 41/47 integrin antagonist designed to reduce trafficking oflymphocytes into the central nervous system (CNS) 1.户使本产品发表的科研献 Clin Cancer Res. 2015 Oct 15;21(20):4642-51.See more customer validations on HYPERLINK / www.MedChemEREFERENCES1. Grove R

5、A, et al. Leukocyte counts in cerebrospinal fluid and blood following firategrast treatment in subjects with relapsing forms ofmultiple sclerosis. Eur J Neurol. 2013 Jul;20(7):1032-42.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792; 021-58955