Sutezolid-PNU-100480-DataSheet-生命科学试剂-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemESutezolidCat. No.: HY-10392CAS No.: 168828-58-8Synonyms: PNU-100480; U-100480; PF-02341272分式: CHFNOS分量: 353.41作靶点: Bacterial作通路: Anti-infection储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 DMSO

2、: 50 mg/mL (141.48 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 2.8296 mL 14.1479 mL 28.2957 mL5 mM 0.5659 mL 2.8296 mL 5.6591 mL10 mM 0.2830 mL 1.4148 mL 2.8296 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。体内实验请根据您的实验动物和给药式选择适当的溶解案，配制前请先配制澄清的储备液，再依次添加助溶剂(为保证实验结果的可靠性，体内实验的

3、作液，建议您现现配，当天使；澄清的储备液可以根据储存条件，适当保存；以下溶剂前的百分 指该溶剂在您配制终溶液中的体积占)：1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.5 mg/mL (7.07 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.5 mg/mL (7.07 mM); Clear solution3. 请依序添加每种溶剂： 10% DMSO 90% corn oil1/2 M

4、aster of Small Molecules 您边的抑制剂师www.MedChemESolubility: 2.5 mg/mL (7.07 mM); Clear solutionBIOLOGICAL ACTIVITY物活性 Sutezolid（PNU-100480）种恶唑烷酮类抗 剂，于治疗结核病。户使本产品发表的科研献 J Pharm Biomed Anal. 2019 May 30;169:196-207.See more customer validations on HYPERLINK / www.MedChemEREFERENCES1. Zhu T, et al. Populat

5、ion pharmacokinetic/pharmacodynamic analysis of the bactericidal activities of sutezolid (PNU-100480) and itsmajor metabolite against intracellular Mycobacterium tuberculosis in ex vivo whole-blood cultures ofpatients with pulmonary2. Wallis RS, et al. Mycobactericidal activity of sutezolid (PNU-100480) in sputum (EBA) and blood (WBA) of patients with pulmonarytuberculosis. PLoS One. 2014 Apr 14;9(4):e94462.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-379