Isosteviol-minus-Isosteviol-DataSheet-生命科学试剂-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEIsosteviolCat. No.: HY-N0872CAS No.: 27975-19-5Synonyms: (-)-Isosteviol; iso-Steviol分式: CHO分量: 318.45作靶点: Reactive Oxygen Species作通路: Immunology/Inflammation; Metabolic Enzyme/Protease; NF-B储存式: Powder -20C 3 years4C 2 yearsIn s

2、olvent -80C 6 months-20C 1 month溶解性数据体外实验 DMSO : 100 mg/mL (314.02 mM)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 3.1402 mL 15.7011 mL 31.4021 mL5 mM 0.6280 mL 3.1402 mL 6.2804 mL10 mM 0.3140 mL 1.5701 mL 3.1402 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存

3、式和期限。体内实验请根据您的实验动物和给药式选择适当的溶解案，配制前请先配制澄清的储备液，再依次添加助溶剂(为保证实验结果的可靠性，体内实验的作液，建议您现现配，当天使；澄清的储备液可以根据储存条件，适当保存；以下溶剂前的百分 指该溶剂在您配制终溶液中的体积占)：1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.75 mg/mL (8.64 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.7

4、5 mg/mL (8.64 mM); Clear solution1/2 Master of Small Molecules 您边的抑制剂师www.MedChemE3. 请依序添加每种溶剂： 10% DMSO 90% corn oilSolubility: 2.75 mg/mL (8.64 mM); Clear solutionBIOLOGICAL ACTIVITY物活性 异甜菊醇(Isosteviol)甜菊糖的衍物。REFERENCES1. Wong KL, et al. Isosteviol acts on potassium channels to relax isolated aort

5、ic strips of Wistar rat. Life Sci. 2004 Mar 26;74(19):2379-87.2. Wong KL, et al. Isosteviol as a potassium channel opener to lower intracellular calcium concentrations in cultured aortic smooth musclecells. Planta Med. 2004 Feb;70(2):108-12.3. Wong KL, et al. Antiproliferative effect of isosteviol on angiotensin-II-treated rat aortic smooth muscle cells. Pharmacology.2006;76(4):163-9.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;