Bendazac-DataSheet-生命科学试剂-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEBendazacCat. No.: HY-17480CAS No.: 20187-55-7分式: CHNO分量: 282.29作靶点: Others作通路: Others储存式: Please store the product under the recommended conditions inthe COA.溶解性数据体外实验 DMSO : 250 mg/mL (885.61 mM; Need ultrasonic)Mass Solvent1 m

2、g 5 mg 10 mg Concentration制备储备液1 mM 3.5425 mL 17.7123 mL 35.4246 mL5 mM 0.7085 mL 3.5425 mL 7.0849 mL10 mM 0.3542 mL 1.7712 mL 3.5425 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。体内实验 请根据您的实验动物和给药式选择适当的溶解案，配制前请先配制澄的储备液，再依次添加助溶剂(为保证实验结果的可靠性，体内实验的作液，建议您现现配，当天使；澄的储备液可以根据储存条件，适当保存；以下溶剂前的百分指该溶剂在您配制终溶液中的

3、体积占)：1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.08 mg/mL (7.37 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% corn oilSolubility: 2.08 mg/mL (7.37 mM); Clear solutionBIOLOGICAL ACTIVITY物活性Bendazac种氧酸，具有抗炎、抗过敏、利胆和抗脂的特性。Bendazac 阻蛋质变性，延缓内障1/2 Master of Small Molecules 您边的抑制剂师

4、www.MedChemE的发过程。体外研究 Bendazac is an anti-inflammatory agent endowed with protein antidenaturant properties effective for variousinflammatory skin conditions. Bendazac has been shown to be a strong reacting substrate in a chemicaloxidizing system, which mimics a physiological pathway of hydroxy radi

5、cal generation 2.By using EPR spectroscopy of spin-labelled bovine serum albumin (BSA), Bendazac was shown to preventthe BSA denaturation induced by urea, heat and free radicals produced in the xanthine/xanthine oxidasesystem 2.REFERENCES1. Balfour JA, et al. Bendazac lysine. A review of its pharmac

6、ological properties and therapeutic potential in the management of cataracts.Drugs. 1990;39(4):575-596.2. Guglielmotti A, et al. Radical scavenger activity of bendazac, an anticataract non-steroidal anti-inflammatory agent. Pharmacol Res.1995;32(6):369-373.3. Musci G, et al. Mechanism of the scavenger-like activity of bendazac. Drugs Exp Clin Res. 1987;13(5):289-292.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel