Nandrolone-phenylpropionate-DataSheet-生命科学试剂-MedChemExpress

Hotline:400-820-3792Inhibitors•ScreeningLibraries•Proteinswww.MedChemENandrolonephenylpropionateCat.No.:HY-101767CASNo.:62-90-8分⼦式:C₂₇H₃₄O₃分⼦量:406.56作⽤靶点:AndrogenReceptor作⽤通路:Others储存⽅式:Powder-20°C3years4°C2yearsInsolvent-80°C6months-20°C1month溶解性数据体外实验DMSO:100mg/mL(245.97mM;Needultrasonic)MassSolvent1mg5mg10mgConcentration制备储备液1mM2.4597mL12.2983mL24.5966mL5mM0.4919mL2.4597mL4.9193mL10mM0.2460mL1.2298mL2.4597mL请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；⼀旦配成溶液，请分装保存，避免反复冻融造成的产品失效。储备液的保存⽅式和期限：-80°C,6months;-20°C,1month。-80°C储存时，请在6个⽉内使⽤，-20°C储存时，请在1个⽉内使⽤。体内实验请根据您的实验动物和给药⽅式选择适当的溶解⽅案。以下溶解⽅案都请先按照InVitro⽅式配制澄的储备液，再依次添加助溶剂：(为保证实验结果的可靠性，澄的储备液可以根据储存条件，适当保存；体内实验的⼯作液，建议您现⽤现配，当天使⽤；以下溶剂前显⽰的百分⽐指该溶剂在您配制终溶液中的体积占⽐；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的⽅式助溶)1.请依序添加每种溶剂：10%DMSO>>90%(20%SBE-β-CDinsaline)Solubility:≥2.5mg/mL(6.15mM);Clearsolution1/2MasterofBioactiveMolecules—您⾝边的抑制剂⼤师www.MedChemE2.请依序添加每种溶剂：10%DMSO>>90%cornoilSolubility:≥2.5mg/mL(6.15mM);ClearsolutionBIOLOGICALACTIVITY⽣物活性Nandrolonephenylpropionate，19-nortestosterone的衍⽣物，⼀种合成代谢类醇，可促进蛋⽩质合成。Nandrolonephenylpropionate⽤于缓解组织分解代谢，可以⽤于⾻质疏松症和特纳综合征的研究。体内研究Nandrolonephenylpropionate(4.0mg/kg/d;daily;for14days)treatmentsignificantlyincreasestheweightgainofrats.Nandrolonephenylpropionatetreatmentincreasesthemixedmuscleproteinfractionalsyntheticrate(FSR).AndthemusclefreecathepsinDactivityissignificantlyincreasedbyNandrolonephenylpropionatetreatment,indicatingincreasedmuscleproteindegradation,totalcathepsinDactivityisunchanged[1].REFERENCES[1].NWDumelow,etal.Effectofnandrolonephenylpropionateonproteinmetabolisminrats.HormMetabRes.1985Aug;17(8):431.[2].KNoda,etal.Effectsoftheanabolicsteroidnandrolonephenylpropionateoncraniofacialgrowthinrats.JMorphol.1994Apr;220(1):25-33.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-