中医药学循证医学文献阅读课件

中医药学循证医学文献阅读SystematicReview系统评价Ginkgo银杏

整理ppt中医药学循证医学文献阅读SystematicReview整1记忆医学术语方法之一NoChineseassimpleasoneword复杂学名记住中文即可整理ppt记忆医学术语方法之一NoChinese整理ppt2GlossaryGinkgoBiloba

[5^iNk^Eu]

银杏树maidenhair[5meIdEnheE]

掌叶铁线蕨intention-to-treatanalysis意向治疗分析neurotransmitter[7njuErEtrAns5mitE]神经递质bias[baiEs]prejudice

偏见depression[di5preFEn]sadness

沮丧抑郁tinnitus[ti5naitEs]

ringingintheears

耳鸣viscosity[vis5kCsiti]stateofbeingthick

粘性整理pptGlossaryGinkgoBiloba[5^iNk^E3Ginkgo[5^iNk^Eu]整理pptGinkgo[5^iNk^Eu]整理ppt4maidenhair

掌叶铁线蕨(少女秀发蕨)整理pptmaidenhair掌叶铁线蕨(少女秀发蕨)整理ppt5意向治疗分析整理ppt意向治疗分析整理ppt6neurotransmitter[7njuErEtrAns5mitE]神经递质整理pptneurotransmitter[7njuErEtrAns7Prejudice

偏见Bias[baiEs]整理pptPrejudice偏见整理ppt8Sadness抑郁Depression[di5preFEn]整理pptSadness抑郁整理ppt9Ringingintheears耳鸣Tinnitus[ti5naitEs]整理pptRingingintheears耳鸣Tinnitus整10Stateofbeingthick粘性viscosity[vis5kCsiti]整理pptStateofbeingthick粘性整理ppt11记忆公共英语单词方法之一NoChineseassimpleasonewordPlainEnglish（简朴英语）整理ppt记忆公共英语单词方法之一NoChinese整理ppt12Glossaryrobust[rE5bQst]strong

精力充沛的substantive[5sQbstEntiv]large

大量的cognitive[5kC^nitiv]

gettoknow

认知的

modification[7mCdifi5keiFEn]makechange

修正Unconfounded[kEn5faundid]notconfuse

不糊涂的inconsistent[7inkEn5sistEnt]contradictory

不一致整理pptGlossaryrobust[rE5bQst]stron13Strong精力充沛的Robust[rE5bQst]整理pptStrong精力充沛的整理ppt14Notconfuse不糊涂的Unconfounded[kEn5faundid]糊涂的

confounded[kEn5faundid]整理pptNotconfuse不糊涂的整理ppt15Contradictory不一致inconsistentshape[7inkEn5sistEnt]整理pptContradictory不一致整理ppt16GlossaryGinkgoBiloba白果(中文即可)Maidenhair掌叶铁线蕨(中文即可)Cognitivegettoknow

Substantive

largeAmendmentimproveDepressionsadnessTinnitusringingintheears

Viscositystateofbeingthick整理pptGlossaryGinkgoBilobaAmendment17《医学英语新教程》第30章-p234–阅读16句子Ginkgo银杏整理ppt《医学英语新教程》第30章-p234–阅读16句子整18《医学英语新教程》第30章-p234–阅读16句子CochraneLibrary系统综述文摘整理ppt《医学英语新教程》第30章-p234–阅读16句子整19LearningObjectivesofSystematicReviewTomasterTitleAuthorStructureofSRResultConclusion

ToknowaboutIntroductionBackgroundObjectiveSearchstrategy掌握整理pptLearningObjectivesofSystema20标题(十分简洁)GinkgoBilobaforcognitiveimpairmentanddementia白果治疗认知损害与痴呆症（Cochrane系统综述）掌握整理ppt标题(十分简洁)GinkgoBilobafo21标题(十分简洁)GinkgoBiloba

for

cognitiveimpairmentanddementia白果治疗认知损害与痴呆症（Cochrane系统综述）掌握整理ppt标题(十分简洁)GinkgoBilobafo22标题固定句式:中心词＋for短语掌握整理ppt标题固定句式:中心词＋for短语掌握整理ppt23当代(科技)医学英语特点Controlledlanguage整理ppt当代(科技)医学英语特点Controlledlanguag24作者（≥2）BirksJGrimleyEvansJ掌握整理ppt作者（≥2）BirksJ掌握整理ppt25（Cochrane综述文摘）CochraneReview‖SystematicReviewAbstract整理ppt（Cochrane综述文摘）CochraneReview26StructureofCochraneReveiwIntroductionBackgroundObjectiveSearchstrategySelectioncriteriaDatacollectionandanalysisMainresultsReview’sconclusion掌握整理pptStructureofCochraneReveiwIn27StructureofCochraneReveiwIntroduction引言BackgroundObjectiveSearchstrategy检索策略Selectioncriteria选择标准Datacollectionandanalysis数据收集与分析Mainresults主要结果Review’sconclusion综述者结论掌握整理pptStructureofCochraneReveiwIn28引言(修订,截至,被动)Asubstantive

amendmenttothissystematicreviewwaslastmadeon26August2002.此系统综述的实质性修改截止2002年8月26日。整理ppt引言(修订,截至,被动)Asubstantiveame29Background

origin起源currentstatus现况mechanism机制掌握整理pptBackgroundorigin起源掌握整理ppt30Background–originExtractsoftheleavesofthemaidenhairtree,Ginkgobiloba,havelongbeenusedinChinaasatraditionalmedicineforvariousdisordersofhealth.在中国，从掌叶铁钱蕨白果树叶精华作为传统药物，长期用于治疗各种疾病。

掌握整理pptBackground–originExtractsof31Background–status②

Astandardizedextract

iswidely

prescribedinGermanyandFranceforthetreatmentofarangeofconditionsincludingmemoryandconcentrationproblems,confusion,depression,anxiety,dizziness,tinnitusandheadache.

掌握整理pptBackground–status②Astanda32背景–现况②一种广泛用于德国与法国的标准萃取物可治疗多种疾病，包括记忆与思想集中病症、意识模糊、抑郁、焦虑、头晕、耳鸣与头痛。

掌握整理ppt背景–现况②一种广泛用于德国与法国的标准萃取物可治疗多种33Background-mechanism③Themechanismsofactionarethoughttoreflecttheactionofseveralcomponentsoftheextractandincludeincreasing

bloodsupplybydilatingbloodvessels,reducingbloodviscosity,modificationofneurotransmittersystems,andreducingthedensityofoxygenfreeradicals.

掌握整理pptBackground-mechanism③Themech34背景–机制③有人认为，若干成分的作用机制是扩张血管、降低血液粘滞度、改善神经递质系统，以及减少氧游离基密度而增加血供

掌握整理ppt背景–机制③有人认为，若干成分的作用机制是扩张血管、降低353.Objective-explicit鲜明

Theaimofthereviewistoassesstheefficacyandsafety

ofGinkgobilobaforthetreatment

ofpatientswithdementiaorcognitivedecline.本综述目标是评估白果治疗痴呆症或认知功能减退的有效性与安全性。

掌握整理ppt3.Objective-explicit鲜明The36Searchstrategy–3T

TimeTypesTerms整理pptSearchstrategy–3TTime整理ppt37Strategy–Time&Types

Trialwereidentifiedon26June2002throughasearchoftheCDCIG……整理pptStrategy–Time&TypesTr38synonym同义词&asterisk*

Thesearchtermsusedwereginkgo*,tanakan,EGB-761,EGB761and"EGB761".所用检索术语为ginkgo*、tanakan、EGB-761、EGB761与“EGB761”。整理pptsynonym同义词&asterisk*The39Selectioncriteria-phrase+clauseAllrelevant,unconfounded,

randomized,double-blindcontrolledstudies,inwhichextractsofGinkgobilobaatanystrengthandoveranyperiodwerecomparedwithplacebofortheir

effectsonpeoplewithacquiredcognitiveimpairment,includingdementia,ofanydegreeofseverity.整理pptSelectioncriteria-phrase+c40收录标准收录所有与白果萃取物（任何浓度与任何疗程）治疗获得性认知损害（包括任何类型的痴呆症）相关的正规随机双盲安慰剂对照研究文献。

整理ppt收录标准收录所有与白果萃取物（任何浓度与任何疗程）治疗获得性41collection&analysis-metaDataforthemeta-analysesarebasedonreportedsummarystatisticsforeachstudy.供荟粹分析分析的资料取自每个研究的发表总结性统计。

整理pptcollection&analysis-metaDa42Mainresults–先总后分General:1-4Division(benefit):5-7

(thesamesentencepattern)Summary(adverse):8-9掌握整理pptMainresults–先总后分General:1-43Mainresults–先总–概括Overall,thereare

nosignificantdifferencesbetweenGinkgoandplacebointheproportionofparticipantsexperiencingadverseevents.在总体上，接受白果与安慰剂受试者的不良反应事件无显著差异。

掌握整理pptMainresults–先总–概括Overall,44Mainresults–先总-metaThereare

benefits(主语)associatedwithGinkgo(doselessthan200mg/day)comparedwithplaceboatlessthan12weeks(54/63showedimprovementcomparedwith20/63,OR15.32,95%CI

5.90to39.80,P=<0.0001).掌握整理pptMainresults–先总-metaThere45Results–统计判断掌握a/b效应概率阳性数/总数-54/63OR(优势比)阳性概率/阴性概率小样本-数越大，优势比大大样本-数字小，优势比也大95%CI(可信区间)无零，数字大，显著;5.9-39.8有零，≥0即显著P值0.05>P>0.01显著意义≤0.001极显著意义整理pptResults–统计判断掌握a/b效应概率阳性数/总数46Mainresults-先总-meta与安慰剂对照组相比，至少在12周以内显示白果（剂量>200mg/日）相关效益（56/43比20/63，优势比15.32，95%可信区间5.90至39.80，P=<0.0001）。

掌握整理pptMainresults-先总-meta与安慰剂对照组47Mainresults–3divisionCognitionshows…(differentdata.)Activitiesshow…//.Measuresofmoodshow…//.Division–后分(疗效)掌握整理pptMainresults–3divisionCogni48Mainresults–division-metaThereare

benefits(主语)associatedwithGinkgo(doselessthan200mg/day)comparedwithplaceboatlessthan12weeks(54/63showedimprovementcomparedwith20/63,OR15.32,95%CI5.90to39.80,P=<0.0001).掌握整理pptMainresults–division-metaT49samepatternwithdifferentsubjectsanddataCognitionshowsbenefitforGinkgo(doselessthan200mg/day)comparedwithplaceboat12weeks(SMD-0.57,95%

CI-1.09,-0.05,P=0.03,randomeffectsmodel).

掌握整理pptsamepatternwithdifferentsu50samepatternwithdifferentsubjectsanddataActivitiesshowsbenefitforGinkgo(doselessthan200mg/day)comparedwithplaceboat12weeks(SMD-0.57,95%

CI-1.09,-0.05,

P=0.03,randomeffectsmodel).

掌握整理pptsamepatternwithdifferentsu51samepatternwithdifferentsubjectsanddataMeasuresofmood…showsbenefitforGinkgo(doselessthan200mg/day)comparedwithplaceboat12weeks(SMD-0.57,95%CI-1.09,-0.05,P=0.03,randomeffectsmodel).

掌握整理pptsamepatternwithdifferentsu52当代(科技)医学英语特点Controlledlanguage整理ppt当代(科技)医学英语特点Controlledlanguag53Reviewers‘conclusionsMeritsImperfectProspect掌握整理pptReviewers‘conclusionsMerits54Reviewers‘conclusions–优点Ginkgobilobaappearstobesafeinusewithno

excesssideeffectscomparedwithplacebo.应用白果相对安慰剂无过度副作用，显得(似乎)安全。掌握整理pptReviewers‘conclusions–优点Gin55Reviewers‘conclusions–说明Manyoftheearlytrialsusedunsatisfactorymethods,weresmall,andwecannot

excludepublicationbias.许多早期试验应用效果不满意者多为小型研究,综述者不能排除论文偏倚。掌握整理pptReviewers‘conclusions–说明Man56Reviewers'conclusions-优点Overallthereis

promisingevidenceofimprovementincognitionandfunctionassociatedwithGinkgo.总体上讲，白果改善认知与功能依据前景良好。掌握整理pptReviewers'conclusions-优点Over57Reviewers‘conclusions–不足However,thethreemoremoderntrialsshow

inconsistentresults.然而，有３个以上当代临床试验的结果不一致。掌握整理pptReviewers‘conclusions–不足How58Reviewers’conclusions–展望Thereisneedforalargetrialusingmodernmethodologyandpermittinganintention-to-treatanalysistoproviderobustestimatesofthesizeandmechanismofanytreatmenteffects.尚需应用现代的方法学与“意向治疗分析”大型临床试验，以提供任何治疗效应大小的有力依据与机制。掌握整理pptReviewers’conclusions–展望The59Summary–keypointsTitle:干预+for+病症Author:

≥2,independently

StructureofSR:8sectionsConclusion:merits;imperfect;p