Pancuronium-dibromide-Standard-DataSheet-生命科学试剂-MCE

Hotline:400-820-3792Inhibitors • ScreeningLibraries • Proteinswww.MedChemEPancuroniumdibromide(Standard)Cat.No.:HY-B0429RCASNo.:15500-66-0分子式:C₃₅H₆₀Br₂N₂O₄分子量:732.67作用靶点:nAChR作用通路:MembraneTransporter/IonChannel;NeuronalSignaling储存方式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.溶解性数据体外实验DMSO:≥100mg/mL(136.49mM)H2O:100mg/mL(136.49mM;Needultrasonic)*"≥"meanssoluble,butsaturationunknown.MassSolvent1mg5mg10mgConcentration制备储备液1mM1.3649mL6.8244mL13.6487mL5mM0.2730mL1.3649mL2.7297mL10mM0.1365mL0.6824mL1.3649mLBIOLOGICALACTIVITY生物活性Pancuronium(dibromide)(Standard)是Pancuronium(dibromide)的分析标准品。本产品用于研究及分析应用。Pancuroniumdibromide，一种双季基类固醇，是一种神经肌肉松弛剂。Pancuroniumdibromide通过与乙酰胆碱竞争nACh受体上的结合位点来抑制神经肌肉传递。Pancuroniumdibromide还可抑制心脏毒蕈碱受体并具有拟交感神经作用。REFERENCES[1].ADFryer,etal.Pancuroniumandgallamineareantagonistsforpre-andpost-junctionalmuscarinicreceptorsintheguinea-piglung.1/2 MasterofBioactiveMolecules—您身边的抑制剂大师www.MedChemENaunynSchmiedebergsArchPharmacol.1987Apr;335(4):367-71.EMaestrone,etal.Extracellularpancuroniumaffectssodiumcurrentinchickembryosensoryneurons.BrJPharmacol.1994Jan;111(1):283-7.JRDocherty,etal.Acomparisonoftheeffectsofpancuroniumbromideanditsmonoquaternaryanalogue,ORGNC45,onautonomicandsomaticneurotransmissionintherat.BrJPharmacol.1980;71(1):225-33.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792F