Pyrantel-pamoate-Standard-Pyrantel-embonate-Standard-DataSheet-生命科学试剂-MCE

Hotline:400-820-3792Inhibitors • ScreeningLibraries • Proteinswww.MedChemEPyrantelpamoate(Standard)Cat.No.:HY-12640RCASNo.:22204-24-6Synonyms:Pyrantelembonate(Standard)分子式:C₃₄H₃₀N₂O₆S分子量:594.68作用靶点:Parasite;nAChR;Antibiotic作用通路:Anti-infection;MembraneTransporter/IonChannel;NeuronalSignaling储存方式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.溶解性数据体外实验DMSO:20.83mg/mL(35.03mM;ultrasonicandwarmingandheatto70°C)SolventMass1mg5mg10mgConcentration制备储备液1mM1.6816mL8.4079mL16.8158mL5mM0.3363mL1.6816mL3.3632mL10mM0.1682mL0.8408mL1.6816mLBIOLOGICALACTIVITY生物活性Pyrantel(pamoate)(Standard)是Pyrantel(pamoate)的分析标准品。本产品用于研究及分析应用。Pyrantelpamoate(Pyrantelembonate)是一种口服有效的驱虫剂，也是烟碱乙酰胆碱受体(nAChR)激动剂。Pyrantelpamoate可引起寄生虫的痉挛性肌肉麻痹。Pyrantelpamoate可用于寄生虫感染的研究，比如蛔虫病、钩虫感染、肠虫病(蛲虫感染)、毛霉菌病和旋毛虫病。IC50&TargetParasites[1][2].REFERENCES1/2 MasterofBioactiveMolecules—您身边的抑制剂大师www.MedChemEMartinRJ,et,al.OxantelisanN-type(methyridineandnicotine)agonistnotanL-type(levamisoleandpyrantel)agonist:classificationofcholinergicanthelminticsinAscaris.IntJParasitol.2004Aug;34(9):1083-90.TrittenL,et,al.InvitroandinvivoefficacyofMonepantel(AAD1566)againstlaboratorymodelsofhumanintestinalnematodeinfections.PLoSNeglTropDis.2011Dec;5(12):e1457.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792Fax: