铜对邻苯二甲酸二乙酯与牛血清白蛋白作用机制影响的光谱学

-，且反应是自发进行的。二者均会改变BSA的二级结构。紫外光谱实验和红外光谱实验结果均表明：Cu/DEP会使BSA的二级结构发生改变。对BSA各二级结构的改变进行定量分析发现，Cu/DEP均使BSA的α-螺旋、无规则卷曲和β-折叠的含量降低，而反平行β-折叠、β-转角的含量增加。对二元体系和三元体系的实验数据进行分析得知，三元体系与二元体系相比，Cu的共存会影响DEP与BSA的结合机制，甚至会使BSA的二级结构发生更大的变化。

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