CPHI -CPHI 米兰展会总结报告：来自制药业核心的关键见解 CPHI Milan Wrap-Up Report Key Insights from the Heart of Pharma

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CPHIMilanWrap-UpReport:

KeyInsights

fromtheHeartofPharma

35th

Anniversary

35yearsattheheartofPharma

35

th

Anniversary

Celebratingits35thedition,CPHIMilanwasheld8–10October,2024atthehistoricFieraMilanoexhibitioncentre.Bringingtogetherover60,000attendeesworldwide,2,400exhibitingcompaniesand150internationalexpertspeakers,CPHIMilanconnectedtheglobalpharmaceutical

supplychainfor3daysofinnovationandthoughtleadership.

CPHIOnlineareproudtobringyouthefirsteditionoftheCPHI

Wrap-UpReport,featuringkeyinsightsfromCPHIMilanandthe

widerpharmaceuticalindustry.Exclusivecontentfromtheshowfloor,conferencetheatres,andexhibitinghubsshowcasethepowerofin-personconnectionandcollaboration.

ThisreportalsofeaturesexclusiveinterviewswithexpertspeakersfromsuchcompaniesasPolpharma,DaiichiSankyo,Moderna,theEuropeanCommission,Novartis,andmanymore.

Whetheryou’relookingtorelivetheCPHIexperience,orcatchuponallthebuzzyoumissedattheevent,thisreportisyourexclusivetickettoallkeyfindingsatCPHIMilan.

ContentsCPHI--·····-

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01Editor’snote

02CPHIAwardsand

CPHICelebration2024

03OnTrackwithCPHIMilan

TrackSponsors

04SpeakerDeepDives

05ConferenceSessions:

SilentTheatres,Buzzing

Conversations

06CustomerInsights:Whatthe

CPHICommunityisSaying

07PharmaTrends

OutlookPreview:

RoundtableRoundup

08Spotlighton

SustainabilityatCPHI

09Start-UpMarket

10TakingCareofOurselves

andEachOther

11Seeyounextyear!

12References

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Editor’sNote

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01Editor,sNote

Editor’sNote1/2

WeontheCPHIContentTeamaredelightedtobringyouourfirsteverCPHIPost-ShowReport,atestamentto

thehardworkanddedicationoftheentireCPHIteaminbringingthe35theditionoftheshowtoMilan.

2024hasbroughtmanyopportunitiesandchallenges

tothepharmaceuticalindustrythroughouttheyear.Asweobservethecontinuedprogressionoftherapeutic

areassuchasweight-lossanddiabetestreatments,

oncologydrugs,andvaccines,wearealsowitnessing

potentialhurdlesinglobalmanufacturingaswellas

newopportunitiesinregionalmarkets[1].Whatever

thechallenges,weunderstandthatbringingthe

pharmaceuticalcommunitytogetherandcollaboratingacrossbordersformsakeycomponentofsuccessfor

innovationinpharma,avaluewehaveinfusedintoeachofourCPHIshowsaroundtheworld.

SustainabilityanddiversitycontinuetobeoverarchingthemesforallourCPHIshows.Wearedelightedto

highlighttheseimportanttopicsinallourconferencesessions,aswellasthroughouttheeventitself.

Thisyearwehostedadedicatedsustainabilitytheatre,theSustainableFuturestrack,toactasahometoall

ofoursustainabilitycontentatCPHIMilan.Thetopicofsustainabilityhasbeenaconsistentlyimportantfeatureofouronsitecontentoverthepastfewyears,andit

seemedonlyrighttogiveevenmoreofaplatformforthisfield,asoneofthemosturgentandpressingissuesfacingthepharmaceuticalindustryandglobalhealthtoday.

Thethemeofsustainabilitydoesn’tjustfitintoouragenda,it’spartoftheveryfabricoftheshow,veryliterallywhenitcomestotheexhibitionstands.

Our

BetterStandsProgramme

encouragestheuse

ofsustainablestands,standsthataremadeoutof

recycledandreuseablematerials,whicharebuiltwith

theideaofusingthemyearonyear.Theconferencealsoencourageswastereductionwherepossible,reuseablebottles,lessprintedmaterials,moredigitalsignage,andcollectionoffoodwaste.

Tofurtheraddresstheimportanceofdiversity,equity,and

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01Editor,sNote

Editor’sNote2/2

inclusion,theCPHIPharmaAwardshaveaddedtwonewcategoriestotheroster.The‘WomanoftheYear’awardandtheFutureLeaderawardrecognisethecontributionsandinnovationsofadiversegroupofindividualsinthe

pharmaceuticalindustry,andweatCPHIareproudtocelebratetheirachievementswithall[2].

AtCPHI,wearededicatedtoconnectingprofessionalsthroughoutthepharmaceuticalsupplychain,bothatoureventsandthroughouttheyearwithourdigital

marketingofferings.Weareproudtohavepublished

fourTrendReportsthislastyear,withtwomorecoming

up:theCPHIMiddleEastBiotechReportandourannual

PharmaTrendsOutlookfor2025.AswecontinuetogrowandmeettheneedsoftheB2Bpharmaceuticalsector,

wehopethatthisCPHIMilanPost-ShowReportwillenablealltounderstandthebiggesttrendsandconversations

happeningthroughoutthepharmaceuticalindustrytoday.

Thankyoutoallwhoorganised,attended,exhibited,orsponsored!

VivianXie

Editor

Pharma

LucyChard

DigitalEditorPharma

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CPHIAwardsand

CPHICelebration2024

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02CPHIAwardsandCPHICelebration2024

CPHIAwardsand

CPHICelebration2024

Thisyear,theCPHIMilanPharmaAwardswereexcited

topresenttheWomanoftheYearawardandthe

FutureLeaderawardtofosteracultureofinclusionandrecognisedifferentperspectivesonchallengesfacedbythepharmaceuticalindustry.TheawardswerepresentedtothewinnersattheCPHIMilanPharmaAwardson

October8,2024.

Additionally,wewereexcitedtointroduceanew

elementtoourflagshipCPHIevent-CPHICelebration

isournewesttakeontheannualPharmaAwards

andNetworkingParty!CPHIeventsarebuiltaround

connectionsforgedbetweencolleagues,partners,and

peersfromacrosstheglobe.CPHICelebrationhighlightedtheimportanceoftheseconnectionswithanexclusive

eveningoftop-levelnetworking,drinks,andcanapes

againstabackdropofinnovation.WithacuratedguestlistofexhibitorsandVIPs,wecelebratedthe2024

CPHIPharmaAwardswinnersandnetworkwiththeleadingvoicesandbrightestmindsinourindustry!

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02CPHIAwardsandCPHICelebration2024

WomanoftheYear

Thisawardaimstorecognisethewomenleadersin

pharmawhoinspireanduplifttheirpeersandcolleagueswithacommitmenttodiversity,equity,andinclusion.

CriteriafortheawardareLeadership&Collaboration,

Advancement,Inspiration,andContributiontotheWiderIndustry.Thesefourcriteriaformthefoundationfrom

whichdeservinggroupsorindividualswillberecognisedandcelebratedfortheirwork.

Throughthisnewcategory,CPHIaimstorecognise

exemplaryleaderswhonotonlypavethewayfor

progression,butalsoplatformingthevoicesofothers

throughtheirleadership.Initiativesandprojectsthat

promoteandempowerunderrepresentedcommunitieswillbehighlighted.Groupsorindividualswhoexemplifythefacilitationofopportunitiesforwomenintheindustryarewhatthisawardhopestorecogniseandendorse

asrolemodelswithinboththeirfieldandthewider

pharmaceuticalindustry.Whetherthroughmentorship,volunteering,employeeinitiatives,orleadershipand

coaching,theserolemodelswillhavecontributedtothediversificationofthepharmaceuticalindustry.

“Overthepastyear,acrossallmajorindustries-film,television,music,health,automotivetonameafew-womenareshowingthattheycontinuetobeaforcetoreckonwith!Withthenumberofwomenexecutivesinpharmaexpectedtoreach40%by2027(asnoted

byPharmE),THISiswhyCPHIWomenissuchanimportantrecognitiontocelebratethewomeninpharmaandbiotechcompaniessecuringaseatat

thetable.”

DemetriaJohnson,CDP,D&IEarlyinCareerPartner,Americas,Genentech

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Byrecognisingtheoutstandingworkofallapplicants

andnominees,CPHIhopestofurthertheconversationondiversityandinclusioninthepharmaceuticalindustry.

Education,recognition,andcollaborationiswhatmakesthisawardatenantofCPHI’scoreprinciples.

“Thereisahugeroomformore(gender)diversityinpharmaandbiopharma–particularlyinleadershiproles.Therefore,weneedmorefemalerolemodels,

andweneedtomakethemmorevisible.Youcan’tbewhatyoucan’tsee.”

ThomasKern,ManagingPartner,Vinc–LifeSciencesStrategicTransactionAdvisory,CPHIMilanAwardJuror

“RecognisingtheCPHIWomenoftheYearisn’tjust

aboutcelebratingindividualachievements-it’s

abouthonouringtheresilience,ingenuity,andimpactofglobalwomenacrossdiversepharmafieldsand

backgrounds.Thisawardsymbolisesourcollectivecommitmenttogenderequalityandempowerment,showcasingthevitalcontributionsofwomento

societyandinspiringfuturegenerationstobreakbarriersandpursuetheirdreams.”

SanobarSyed,BusinessStrategyandCommercialExpert,CPHIMilanAwardJuror

CongratulationstoJuliaTsetisofOFETPharmaceuticalGroup!

CEOoftheOFETPharmaceuticalGroup,Tsetiswas

nominatedasatrulyvisionarywoman,andsomeone

wholeaves“anindeliblemarkontheglobalhealthcare

landscape”.Tsetisdemonstratesapassionate

commitmenttothewiderpharmaceuticaland

healthcareindustry,throughseveralventuresincluding

UnitedNationsHighCommissionerforRefugees,and

winningawardsforcorporatesocialresponsibilityandforsustainability.

FutureLeader

Agemaybejustanumberbutwithnewgenerationsofpharmaceuticalprofessionalscomesnewideasand

perspectives.TheFutureLeaderawardaimstorecognisetherisingstarsinthepharmaceuticalindustrywhoare

bringingfreshapproachestothewiderindustry.CriteriaforthisawardincludeLeadership&Collaboration,

PersonalBrand,Recognition,andIndustryInvolvement.

Eachnomineewillhaveanoutstandingrecordasanemergingtalentorleader,whethertheyinspiretheircolleagueswithadditionalrolesandresponsibilities

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oriftheyalreadymanagetheirownteams.Newwaysofthinkinganddoingthingsisavitalpartofbeinga

FutureLeader.Theawardwinnerwillbearolemodelininnovationandoriginalinitiatives.Additionally,theCPHIFutureLeaderwillbeanexemplarycontributortotheircommunityinthoughtleadershiprolesandfurtheringindustryknowledge.

Theywillbecommittedtodevelopingthebroader

pharmaceuticalindustry,participatingessential

conversationspertinenttoallcolleaguesandpartners.

GrantingtheserisingstarsaplatformtoshowcasetheirworkandtalentsisakeypartofCPHI’sethosinupliftingdifferentvoicesinthepharmaceuticalcommunity.TheCPHIMilanFutureLeaderAwardhopestohonourthosebringingafreshapproachtotheindustry.

Whetheryouarealeaderinyourfieldorwishtonominatesomeonedeservingofrecognition,theCPHIPharma

Awardsaredesignedtogiveworldwiderecognitionandglobalexposuretothoseenablingpurposefulchange

andinnovationwithinourindustry.

“TheCPHIAwardsbringtalentandsolutionstogether,allwiththehopetobuildahealthierandmore

sustainablefutureforusall.Iamimmenselyexcitedtogetasmallglimpseofthetrailblazerspavingthewayforpharmaceuticals!”

AnitaVasilevska,TechnicalMarketingManager,IMCD,CPHIMilanAwardJuror

CongratulationstoDrMeganSmythofAlmacSciences!SeniorTeamLeaderSmythdrivesthecompany’s

flowchemistryplatform,everythingfrombusiness

developmenttomarketingstrategiestohightechnicalknowledgeandskills.Smythisalsoaninspiringrole

modelforyoungscientists.

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Thewinnersofthe2024

CPHIPharmaAwardsare...

APIDevelopmentandInnovation

ThewinnerinthiscategoryisLonza,fortheirLonza

AI-EnabledRouteScoutingService.Thetechnology

usescommercialdataandcomputer-aidedsynthesisplanningtechnologytoassistpartnersindeveloping

syntheticpathwaystodrugcandidates,andbuildmoreresilientandfasterR&Dstartuptimes.

CEOoftheYear

ThewinnerhereisGuyClark-CEOofCNXTherapeutics.ClarkbecameCEOinJanuary2022,sincethenthe

companyhasgrownunderhisleadership.Thecompanyhasincreasedinrevenue,countryexpansion,employees,andnewfocusesincludingwellnessandsustainability

withinthecompany.

DrugDeliveryandDeviceInnovation

AdarePharmaSolutionshavecreatedasprinkle-formulateddrugproduct,touseinthetreatmentof

tremorsandotherpersistentanduncontrollablebodymovements.Thesprinkleformulationenablesflexibleadministration,meaningitismucheasierforpatientstoconsume.Theproductkeepsthepatientandthe

caregiverattheforefrontofthedesign.

FinishedFormulation

TheUniLayerStrawDeliverySystemfromUnistrawCorp.gainstheawardforFinishedFormulation.TheUniLayer

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StrawDeliverySystem2mgLoperamideHClstrawis

designedtoassistwithcomplianceforpeopleofallages.Themedicationisdose-controlledthroughthequantityofwaterconsumedtoavoidmisuse.Itisalsoamore

sustainableandaccessiblesolution.

FutureLeader

OurfirstwinnerintheFutureLeadercategoryis

DrMeganSmyth,SeniorTeamLeaderforAlmac

Sciences.Smythisakeydriverofthecompany’s

innovativeflowchemistryplatform,frombusiness

developmentandstrategy,marketing,recruitmentas

wellashightechnicalcapabilities.Smythalsoactsasaninspiringrolemodeltoyoungscientists.

ManufacturingExcellence

FromRheaVitafortheircontinuousfreeze-dryingsystemallowingasepticGMPproduction.Thesystemallows

ashiftinlyophilisationmanufacturingfrombatchto

continuous,takingtherawmaterialsthroughtothe

finishedproductinanuninterruptedproductionchainforbiopharmaceuticals.Itistheworld’sfirstcontinuousfreeze-dryingGMPsystem.

Prodigyisasuiteofapplicationsdevelopedby

ProPharmaGroup.ProdigyusesAIandmachinelearningtoautomateandstreamlinevariousmanuallyintensiveactivitiesacrossregulatory,medical,andclinical

operations.

Thesystemhasseveralkeyfeaturesthatmakeitunique,including:AI-EnabledDocumentQualityControl,Real-

TimeClinicalDataVisualisation,RegulatoryInsights

andApprovals.Thesoftwarewillacceleratethe

developmentoflife-savingtherapiesfromdiscoverytocommercialisation

PackagingandMachinery

Cere®ScreenDigitalDisplayLabelfromWestRockisthewinnerinthiscategory.Thelabellingsystemisdesignedtohelpclinicaltrialsupplyandpatients.Thedigital

displaylabelfacilitatesasecure,remote&realtime,capabilitytoupdatecustomisablelabelcontent.

Withmultiplepageswithascrollingfunctionalitythelabelcanaccommodateallnecessaryinformation,aswellasbeingproducedinseveraldifferentlanguages.

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SupplyChainExcellence

QYOBOGmbHwinstheawardinthiscategoryfor

TheQYOBOplatform.Combiningdatafromover250

sourcesintoasingleplatform,QYOBOoffersaclearviewofpharmaceuticalsupplychainsformorethan2milliondrugsinover40countries.

Theplatformenablesuserstotakequick,informed

actionsbycombiningsupplychaininformationwith

globaldrugshortagesandmarketingauthorisation

data,enablingtheanticipationofrisksandmitigatedrugshortages.

Start-UpInitiative

Nebu~FlowNebuliser,fortheEfficientInhalaitonDeliveryofBiologics,fromAcu-FlowLtd.Thepatentedtechnologyisasoftaerosolisationmethodcapableofdispersing

high-valueRNAformulations,preservingtheiractivityforefficientinhalationtherapy.

Thetechnologyusesultrasoundwaves,givingauniqueabilitytotargetthealveolarregionofthelungs.

AttheHeartofPharma

FoxChaseCancerCenterandWestPharmaceuticalServiceswinforthecommunity-servingaward,

AttheHeartofPharma.Thepartnershipbringscancer

screeningstoresidentsofPennsylvaniaviaamobile

screeningunit(MSU).Duringtheperiodof2019-2023,theprogrammehasprovidedbreastcancerscreeningsto

7,457womenandnavigated285patientsintofollow-upcareatFCCC.Theserviceprovidesaccesstodiagnosis

andtreatmentthatmightotherwisebedifficultforcertainpopulations,andkeepstheoverallhealthandwellnessofthecommunitiesattheforefrontofwhattheydo.

Sustainability

EvonikIndustriesAGwinsthecovetedawardforSustainabilitythisyearwiththeirPhytoSquene®

plant-basedsqualeneforparenteralapplications.

PhytoSquene®istheworld’sfirstGMP-quality,plant-

derivedsqualene.Itoffersasustainableandhigh-qualityalternativetotraditionalshark-derivedsqualene,meetingtheneedforsustainablysourcedpharmaceutical-grade

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squalene.Thishelpsprotectlifebelowwater.Decliningsharkpopulationsislinkedtotheoveralldeclineof

biodiversity.Therefore,PhytoSquene®contributestothepreservationofmarinebiodiversity.

AcceleratingInnovation

FromAustinPx,theirKinetiSol(™)Technologywinsfor

acceleratinginnovation.KinetiSolisafusion-based

processforthemanufactureofamorphoussolid

dispersionsystems.Itenablesthethermalprocessingofheat-sensitiveAPIsandexcipientswithoutdegradationbyreducingcumulativethermalstress.Thetechnologyimprovesexistingdrugdeliverymethodsbutalso

pavesthewayforfuturedevelopments,drivingthe

pharmaceuticalindustrytowardsmoresustainableandeffectivesolutions.

WomanoftheYear

Anothernewawardforthisyear,withJuliaTsetistakingthecrownasourfirstwinner.TsetisisCEOoftheOFET

PharmaceuticalGroup.Nominatedasatrulyvisionarywoman,andsomeonewholeaves“anindeliblemarkontheglobalhealthcarelandscape”.Tsetisdemonstrates

apassionatecommitmenttothewiderpharmaceuticalandhealthcareindustry,throughseveralventures

includingUnitedNationsHighCommissionerforRefugees,andwinningawardsforcorporatesocialresponsibility

andforsustainability.“JuliaTsetisembodiesresilience,

vision,andcompassion.Herlegacyextendsbeyond

corporatesuccess—it’saboutempoweringothers,

advancingscience,andleavingtheworldbetterthanshefoundit”.

CPHI--

CELEBRATN

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OnTrackwith

CPHIMilanTrackSponsors

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OnTrackwith

CPHIMilanTrackSponsors

TheCPHIMilanConferenceTracksbringtogether

speakersfromacrossthepharmaceuticalsupplychaintodiscusstopicsrangingfromManufacturing5.0totheFutureofPharmaceuticalIngredients,toinnovationsin

PackagingandSustainability.WesatdownwithsomeoftheTrackSponsorstoexplorewhyCPHIMilanistheplacetohavethesediscussions.

ThermoFisherScientific:Manufacturing5.0

ThisyearssponsorsfortheManufacturing5.0Track

focusingonthecoretenantsofIndustry5.0,itsevolutionfromIndustry4.0,andhowthepharmaceuticalsector

isadaptingareThermoFisherScientific.Executive

Director,GlobalHeadofTechnical&ScientificAffairsAnilKane,PhD,MBA,spokewithusaboutwhatitmeanttobesponsoringtheManufacturing5.0TrackatCPHIMilan[3].

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1.WhatarethehallmarksofPharma/Manufacturing5.0?

Pharmaandmanufacturing5.0istransforming

drugdevelopmentandproductionbyensuringand

leveragingadvanced,human-centredtechnologies.Thiscombinationshouldnotonlyhelptheindustrybutalso

putspatientsfirst.Incorporatingtechnologieslikeartificialintelligenceandmachinelearningmeansmoretailoredtherapiesandfaster,moreefficientproductionprocesses.Thiscanbringastrongerfocustowardspatient-centric

solutionsbycombiningthestrengthsofbothhumancreativityandmachineefficiency.Pharma5.0hasthepotentialtodriveinnovationwhilemaintainingadeepcommitmenttomeetingindividualpatientneeds.

2.HowdoesManufacturing5.0builduponcurrenttenantsofIndustry4.0?

Industry5.0representsasignificantshiftinhow

manufacturingprocessesareviewedandexecuted.

Industry4.0hasbeenaroundforawhile,andit

revolutionisedproductionwithadvanceddigital

technology,automation,connectivity,andmore.Industry5.0takestheindustryfurtherbyreintroducingthe

humanelementintotheseprocesses.Itemphasisesthepartnershipbetweenhumansandtechnologiessuchas

artificialintelligence,leadingtoamorepersonalisedandvalue-drivenapproachtomanufacturing.

3.Whyarewenowseeingashifttowardsanewmanufacturingrevolution?

Thelandscapeforbringingnewpharmaceuticalproductstomarketisevolvingwiththegrowingcomplexityof

noveltherapies.Globalsupplychainuncertainties,

increasedcompetition,intensifiedregulatoryscrutiny,

andcompressedtimelineshaveforcedpharma

companiestosearchfornewwaysofworking,includingtheintegrationofaugmentedorvirtualrealitytechnologyformoreefficienttraining,andthewidespreadadoptionofcontinuousmanufacturingtoguaranteeproduct

safetyandqualitywithoutsacrificingspeed-to-market.Additionally,majortrendssuchaspersonalisedmedicineandtheriseofartificialintelligencearereshapingthe

market.Thisrequiresincreasedcustomisationand

flexibilityforpharmacompaniestoremaincompetitive.

4.WheredoyouhopetoseeManufacturing5.0developinthenextfewyears?

Overthenextfewyears,itisourhopethatManufacturing5.0willcontinuetoemphasisetheimportanceofpatients

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asthepriorityofthepharmaceuticalmanufacturing

sector.Wealsoanticipatemoreapprovalsforlife-savingtherapiesfordifficult-to-treatdiseases,likecancers

andrarediseases.Webelievethiswillrevolutionisetheresearchanddevelopmentprocessandbringeffectivemedicationstotreatthesediseasestomarket.

PackagingInnovation

The

AllianceofRTU

wascreatedbyfoundingmembersGerresheimer,SCHOTTPharma,andStevanatoGroupasanopenplatformtoshareReady-to-Use(RTU)

advantageswithinthepharmaceuticalindustry.Withamissionstatementofadvancingtheindustry’stransitiontohigh-qualitysterileprimarypackagingwithefficiencyandsafety.InthisTrackSponsorinterview,theydiscussrecentdevelopmentsinpackagingandwhattoexpectfromthePackagingInnovationtrackatCPHIMilan[4].

1.Whatarethelatestdevelopmentsinclinicalvscommercialpackaging?

Givenbiologics’dominanceinthedrugpipeline,the

primaryrequirementforpackagingistoensurestabilityandintegrity.RTUpackaginghasbecomeapreferred

solution,asitminimiseshandling,reducescontamination

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