2-Deoxyuridine-5-monophosphate-disodium-Standard-生命科学试剂-MCE

Hotline:400-820-3792Inhibitors•ScreeningLibraries•Proteinswww.MedChemE2'-Deoxyuridine5'-monophosphatedisodium(Standard)Cat.No.:HY-W011142RCASNo.:42155-08-8分⼦式:C₉H₁₁N₂Na₂O₈P分⼦量:352.15作⽤靶点:EndogenousMetabolite;EndogenousMetabolite;ReferenceStandards作⽤通路:MetabolicEnzyme/Protease;Others储存⽅式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY⽣物活性2'-Deoxyuridine5'-monophosphate(disodium)(Standard)2'-Deoxyuridine5'-monophosphate(disodium)(HY-W011142)的分析标准品。本产品⽤于研究及分析应⽤。2'-Deoxyuridine5'-monophosphate(dUMP)disodium⼀种脱氧核苷酸，通过双底物酶胸苷酸合酶(TS)还原甲化为dTMP(2'-脱氧胸苷5'-单磷酸)。dTMPDNA合成所需的核REFERENCES[1].ZacharyNewby,etal.Theroleofproteindynamicsinthymidylatesynthasecatalysis:variantsofconserved2'-deoxyuridine5'-monophosphate(dUMP)-bindingTyr-261.Biochemistry.2006Jun20;45(24):7415-28.[2].SkouloubrisS,etal.TargetingofHelicobacterpylorithymidylatesynthaseThyXbynon-mitotoxichydroxy-naphthoquinones.OpenBiol.2015Jun;5(6):150015.[3].ZacharyNewby,etal.Theroleofproteindynamicsinthymidylatesynthasecatalysis:variantsofconserved2'-deoxyuridine5'-monophosphate(dUMP)-bindingTyr-261.Biochemistry.2006Jun20;45(24):7415-28.[4].SkouloubrisS,etal.TargetingofHelicobacterpylorithymidylatesynthaseThyXbynon-mitotoxichydroxy-naphthoquinones.OpenBiol.2015Jun;5(6):150015.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792a