2030 年艾滋病预防工作汇报：由国家主导应对行动的全球普及框架

HIVPrevention2030.

AGlobalAccessFrameworkforCountry-LedResponsesDisseminationwebinar,31March2026Withoutsustainedandacceleratedprimaryprevention,2030targetswillbeoutofreachandgainslostSource:UNAIDSestimatesandprojectionsfromAvenirHealth,October2025.Formoreinformationpleasesee:/sites/default/files/2025-04/JC3144_Estimates_Funding_cuts_impact_En.pdfNewHIVinfections:Trendsandprojectionsforthreescenarios,globalTheworld’sHIVresponseatatippingpointProgressmadeintheAfricaregionthroughacombinationoftreatmentandprimarypreventionbut

-largegapsremaintoreachtargets

-progressisunequalbetweencountriesand,

-threatenedbydeclininginvestment2030Target:90%reductioncomparedto2010GlobalAIDSStrategy

2026-2031

2030GlobalAIDSTargetsBoldVisionBy2030,everypersonatriskofHIVwillhaveaccesstoapreventionoptionthatsuitstheirneeds.RealityofaFundingCrisisWewillnotachieveourboldvisionfor2030inaconstrainedenvironmentwithoutsignificanttransformation.Countriesnowneedtoreshapetheirresponsestowardscountry-led,sustainable,well-prioritized,efficientpreventionprograms.->optimallyuseavailableresourcesImpactZoominginon2030programmaticprimarypreventiontargetswithinGASOutputsOutcomesTranslatedinto:95%ofpeoplereachedwithperson-centredpreventionprograms*95%ofcountrydistributionneedmetforcondoms,PrEP,PEP,needles,syringes,OAMT90%ofadolescentsandyoungpeoplereceiveCSE80%ofpeople-centredHIVpreventionprogrammesforkeypopulationsdeliveredbycommunity-ledorganizationsAchievedthroughtrustedhealth,community,virtualandothersectorplatformsforwomen&girls,men&boysinsettingswithhighHIVandfivekeypopulationsNewHIVinfectionsreducedby90%in2030comparedto201090%*ofpeopleinneedofpreventionuseeffectivepreventionoptionsTranslatedintothematictargets:

80%condomusewithnon-regularpartnersUpto80%useofARV-basedprevention–PEP/PrEPincludinglong-actingproductsinlinewithepidemiology**andpeople’schoicesPopulation-specifictargets:90%ofboys&menaccessedVMMCin15prioritycountries95%ofpeoplewhoinjectdrugsusesafeinjectingequipment,50%ofpeoplewhoinjectopioidsonOST95%condomuseatpaidsexamongsexworkersandtheirclients**ForPrEPtargets,indicativeHIVincidencethresholdsbysub-populationswillbeupdatedandsimplified,whilemaintainingtheprincipleofadifferentiatedapproach.HIVtreatmentasprevention:

90%ofallpeoplelivingwithHIVhavesuppressedviralloadsImprovedhealth,community,education&socialsupportsystems,legalenvironments80%HIVpreventionoptionsdeliveredby

community-ledorganizationsOthercriticalHIV,health&developmenttargets

PeopleinneedofHIVpreventionYoungpeopleandadults

(inareaswithelevatedHIV)Keypopulations

(sexworkers,gaymenandothermenwhohavesexwithmen,transgenderpeople,peoplewhoinjectdrugs,peopleinprisonsandotherclosedsettings)PeoplelivingwithHIV95%ofpeopleinneedofpreventionreachedwithHIVprevention*People-centredprogramsinlinewithprogrammaticguidanceincludeservices,accesstopreventionoptions,actionstoaddressstructuralbarriersandtailoredpreventioncommunicationsaddressingbehaviorandnormsDenominatorsPrimaryHIVpreventiontargets40+20by30:ToplinenumericmilestonesforreducingnewHIVinfectionsAlternativepresentation–DONOTCITEThekeyinnovationwillbecountry-ownedneedsestimates&milestonesbasedongranulardata:IllustrativecountryexampleAlternativepresentation–DONOTCITE1.1

MILLION+350

THOUSAND+85

MILLION+>20PERCENT

=

90%ofpeopleinneedusepreventionoptionsPeoplelivingwithHIVaccessingtreatmentPeopleusingPrEPoptionsCondomsofdomesticHIV

fundinggoesto

prevention90%

ofpeoplelivingwithHIVvirallysuppressed

Andthiscouldbetranslatedintodistricttargetsaswell1.3

MILLIONWomen&girls,boys&meninlocationswithhighHIVReachedwithcombinationprevention

Highlyfocusedbehavioral,biomedicalandstructuralelementswithadditionalpopulation-specificsub-targetsforanoptimizedmixofinterventionsandaccessplatforms90%

reductioninnewHIVinfectionsfrom2010to2030

80

THOUSANDKeypopulations

(with9500usingharmreduction)ContributionofotherHIVresponsetargets,enablersandsystems

2024(baseline)20262027202820292030Condoms52million5664728085millionPrEP70000100000220000270000350000350000PEPTBCTBCTBCTBCTBCTBCVMMC120000120000120000120000120000120000Women&girlsinlocationswithelevatedHIVincidence(>0.2%)350000350000550000750000900000900000MenandboysinlocationswithelevatedHIVincidence(>0.2%)200000200000300000350000400000400000SexWorkersreached230002500035000400004500045000MSMreached200002400032000400005000060000TGpeoplereached100015002000300035004000PWIDreachedwithneedles&syringes400060008000950095009500PWIDreceivingOAMT50010002000300040004800Prisonersreached100020003000500060006000IllustrativecountrytargettablebasedongranularneedsestimateStrategicshiftsinthenewframingofpreventionAperson-centred

preventionframeworkButnoteverythingforeveryoneCarefullychosenbiomedical,behavioral,structuralelementsScaledtrustedaccessplatformsAccesspoints

ByinterventionHealthfacilitiesCommunity-ledandotheroutreachPharmaciesKey/higherrisklocationsVirtualspacePrivatesectoroutletsOthergovernmentsectorsDispensersCommunications

Condoms

OralPrEP

PEP

Needles&syringes

Bypopulation

Women&Girls

Men&boys

Gaymen&otherMSM

Sexworkers

Transgenderpeople

Peoplewhoinjectdrugs

NEWSystematicallyplancountryaccessplatformsfordifferentpreventionoptionsandpopulationsDesignwithaviewtoenableself-careFewerresourcesMoreresourcesServicedeliveryapproachesCommunityengagement,leadershipandaccountabilityActionstoaddresshuman-rights&genderrelatedbarriersandcreateanenablingpolicyenvironmentKP-competentpharmaciesKP-competenthealthfacilitiesOtherhealthfacility-basedmodalities:Peernavigation,

KProomsordays,sexualhealthclinicsPeer-ledoutreachinvirtualspacesAdditionalonlineservices

(e-pharmacy,counselling)Peer-ledoutreachinphysicalsettings(differentiatedbasedonneed)Drop-incentresOtherkeyvenuepresence:

Vendingmachines,bars,kiosks,eventsMobileclinicsDedicated

KPclinicsitesOnlineClinicsOutreachAdd…LowerHIVincidenceHigherHIVincidenceEnablersareafoundationthatentailsomeactionsthatdonotrequireextensiveresourcesandothersthatdo.

Thespecificneedsshouldbeconsideredbasedonthecountry’slegalandpolicyenvironmentandresourceavailability.EnablersUpdateddetailed

planningguideavailableExample:PrioritizingaccessplatformsforkeypopulationsMulti-sectorstewardshipofHIVprevention:Keyfunctionsofnationalcoordinating/leadagenciesAnalysis

AnalysetheHIVepidemic&preventionresponse,determinethegapsandneedsStrategyDefineanevidence-basedstrategy,settargetsandmultisectoralactionareasforprogrammes,andaddresspolicy&legalbarriersResourcesDefineresourceneeds&gapsandmobilizeresourcesLeadership&coordinationEstablishpoliticalleadershipandresponsibilityforstewardshipofthemulti-sectoralHIVpreventionresponseCommunicationsPopularizetheurgencyofHIVpreventionandcoordinatecommunicationsSystemdesignDefineasustainablenationalpreventiondeliverysystem,identifystrategicactorsandtheirroles(acrossallpartnersandfundingstreams)ImplementationDriveandfacilitateeffectivemanagementofimplementationatscaleMonitoringMonitor&evaluateanduselearningsforproblem-solvingAccountabilityEstablishandmonitorjointaccountabilityScalableandsustainablepreventionto2030andbeyond.5Psofprioritization

Therightpeople,rightplaces,packages,bestplatforms,pricesRationaleforpreventiontargets–andhowtheyrelatetoHIVincidenceAnewfinancingcontextTotalNeed:US$21.9billionTotalNeed:US$29.3billionFIGURE10.AdjustedResourceNeedsEstimatesforHIVPrevention,2025vs2030([i])

[i].UNAIDS(2021).GlobalAIDSStrategy2021-2026—EndInequalities.EndAIDS.Page103.Onlineat/sites/default/files/media_asset/global-AIDS-strategy-2021-2026_en.pdf&UNAIDS(2025).AIDS,crisisandthepowertotransform:UNAIDSGlobalAIDSUpdate2025.Geneva:JointUnitedNationsProgrammeonHIV/AIDS;2025.Licence:CCBY-NC-SA3.0IGO.113.Onlineat/en/resources/documents/2025/2025-global-aids-updateA45%reductionincostformeeting2030preventiontargetsinlow-andmiddle-incomecountriescomparedtotheresourceneedsestimatefor2025ReductionsincommoditypricesImprovedfocusofprogramsandtargetsThebulkofresourceneedforpreventionisnowinmiddle-incomecountriesAmongtheTop10LMICsforpreventionresourceneed9of10aremiddle-incomecountries8of10areoutsidesub-SaharanAfrica2030PrEPtargetsinLMICsbyincomelevel90%ofthisisSouthAfrica~50%ofthisisMozambique2030CondomtargetsNeedfordifferentiatedtotalmarket/programapproachLargeroleformarketsinhigh-incomeand(upper)middle-incomecountriesKeyroleforinternationalfinancinginlower-incomecountrieswithhighHIVFromneedsestimatestodeliveryandfinancing(illustrativecountrytable)

PreventionoptionsTarget

(illustrative)Program/marketsegment(sharein%ofproductsandpopulationstobereached)Fundingsourceforfree&subsidized(sharein%ofcost)Free(public)Subsidized(socialmarketing)Sold(private/outofpocket)GovernmentDonorsCondoms85million50%30%20%50%30%PrEP(DailyOral)12000080%10%10%30%60%PrEP(Long-acting)230000100%--10%90%PEPTBC60%20%20%50%20%VMMC12000090%-10%50%50%Needles&syringes2.5million80%-20%40%20%OAMT4800100%--80%20%People-centredprogramsandaccessplatformsTarget

(illustrative)FacilityOutreachVirtualGovernmentDonorsWomen&girlsinlocationswithelevatedHIVincidence(>0.2%)90000040%10%50%80%20%MenandboysinlocationswithelevatedHIVincidence(>0.2%)40000010%10%80%80%20%SexWorkersreached4500040%40%20%50%50%MSMreached6000020%10%70%50%50%TGpeoplereached400020%30%50%50%50%PWIDreached1000040%40%20%50%50%Prisoners800080%-20%90%10%Keymilestonesofaroll-outplanfor2030

DueDateNeedsEstimates:RevisepreventiondenominatorsforthoseinneedoftargetedservicesApril2026MethodMixTables:SetannualnumericaccesstargetsperpopulationandinterventionApril2026M&ETools:UpdatetoolstotrackoverallHIVpreventionuse(i.e.,anymethodatlastsex)June2026AccessPlatforms:MappreventionusebypopulationandproductacrossdeliverymodelsJune2026TotalMarketApproach:Analyseviability