Inolitazone-hydrochloride-hydrate-Efatutazone-hydrochloride-hydrate-生命科学试剂-MCE

Hotline:400-820-3792Inhibitors•ScreeningLibraries•Proteinswww.MedChemEInolitazonehydrochloridehydrateCat.No.:HY-14792CCASNo.:1048002-36-3Synonyms:Efatutazonehydrochloridehydrate;CS-7017hydrochloridehydrate;RS5444hydrochloridehydrate分⼦式:C₂₇H₃₀Cl₂N₄O₅S分⼦量:593.52作⽤靶点:PPAR作⽤通路:CellCycle/DNADamage;MetabolicEnzyme/Protease;VitaminDRelated/NuclearReceptor储存⽅式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY⽣物活性Inolitazonehydrochloridehydrate新型PPARγ⾼亲和性激动剂，EC50为Rosiglitazone(HY-17386)的五⼗分之⼀，对于不表达PPARγ的RIE细胞⽆抑制性。IC50&TargetPPARγ户使⽤本产品发表的科研⽂献•IntJOncol.2018Jun;52(6):1991-2000.•FrontMicrobiol.2019Jan8:9:3257.•ExpCellRes.2017Dec15;361(2):246-256.•CancerMed.2018May;7(5):1955-1966.•bioRxiv.2025Oct22.Seemorecustomervalidationsonwww.MedChemEREFERENCES[1].CoplandJA,etal.Novelhigh-affinityPPARgammaagonistaloneandincombinationwithpaclitaxelinhibitshumananaplasticthyroidcarcinomatumorgrowthviap21WAF1/CIP1.Oncogene.2006Apr13;25(16):2304-17.1/2MasterofBioactiveMolecules—您⾝边的抑制剂⼤师www.MedChemE[2].MarlowLA,etal.ReactivationofsuppressedRhoBisacriticalstepfortheinhibitionofanaplasticthyroidcancergrowth.CancerRes.2009Feb15;69(4):1536-44.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792ax:02