L-Methionine-d1-生命科学试剂-MCE

Hotline:400-820-3792Inhibitors•ScreeningLibraries•Proteinswww.MedChemEL-Methionine-d1Cat.No.:HY-N0326S13CASNo.:74334-17-1分⼦式:C₅H₁₀DNO₂S分⼦量:150.22作⽤靶点:Isotope-LabeledCompounds;EndogenousMetabolite;Keap1-Nrf2;Apoptosis作⽤通路:Others;MetabolicEnzyme/Protease;NF-κB;Apoptosis储存⽅式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY⽣物活性L-Methionine-d1氘代标记的L-Methionine(HY-N0326)。L-Methionine⼀种具有⼝服活性的Methionine的L-异构体，Methionine⼀种必需氨酸。Methionine⼀种强肝解毒剂，作为肝脏保护剂。L-Methionine可抑制细胞增殖，诱导细胞凋亡。L-Methionine具有抗肿瘤和抗氧化活性。体外研究Stableheavyisotopesofhydrogen,carbon,andotherelementshavebeenincorporatedintodrugmolecules,largelyastracersforquantitationduringthedrugdevelopmentprocess.Deuterationhasgainedattentionbecauseofitspotentialtoaffectthepharmacokineticandmetabolicprofilesofdrugs.REFERENCES[1].BenavidesMA,etal.L-Methionineinhibitsgrowthofhumanpancreaticcancercells.AnticancerDrugs.2014Feb;25(2):200-3.[2].ErdmannK,etal.L-methioninereducesoxidantstressinendothelialcells:roleofhemeoxygenase-1,ferritin,andnitricoxide.AAPSJ.2005Aug29;7(1):E195-200.[3].WangZ,etal.l-MethionineactivatesNrf2-AREpathwaytoinduceendogenousantioxidantactivityfordepressingROS-derivedoxidativestressingrowingrats.JSciFoodAgric.2019Aug15;99(10):4849-4862.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792ax