脑脊液浆膜腔积液检查【研究荟萃】

1、,Cerebrospinal Fluid (CSF) Examination,1,行业特选,Outline,CSF: colourless liquid that flows through the four cerebral ventricles, subarachnoid space and spinal canal surrounding the brain and spinal cord . CSF cirlulation communicate with blood circulation Adult:90150ml Newborn:10 60ml,2,blood brain bar

2、rier,3,AIMS,中枢神经感染性疾病的诊断与鉴别诊断。 脑血管疾病的诊断与鉴别诊断。 协助脑部肿瘤的诊断。 中枢神经系统疾病的治疗与疗效观察。,4,Contents of examination,General Properties：pressure、color、 Transparency 、 Clots and film Chemical Examination： protein、glucose、chloride Microscopy Bacteriological Examination,5,Pressure,General Properties Adult(lying): 8018

3、0mmH2O， 40-50 drips/min children：40-100mmH2O。 Increase： Intracranial Inflammation：meningitis, cephalitis, myelitis cerebral edema, cerebral hemorrhage, brain tumors Extracranial：hypertension, congestive heart failure Decrease:CSF circulation obstruction, loss or impairment in secretion,6,Color chang

4、es,7,Transparency,Normal :Clear, colorless Clear or Cloudy： Viral Meningitis、Epidemic Encephalitis B or Syphilis in CNS Ground glass opacity：Tuberculous Meningitis Milky turbid：Purulent Meningitis,8,Clots and film,Normal: No clots or film in 24 hours Purulent Meningitis :clots observed in 1-2 hours

5、Tuberculous Meningitis :thin film cover after 1224 hours Subarachnoid obstruction:yellow jelly,9,Protein,Qualitative ：Pandy test：-/ Quantitative ：0.150.45g/L (adult,lumbar puncture),+,+,+,+,Chemical examination,10,Clinical significance,inflammation： PM: TM: VM: Hemorrhage in cranial or subarachnoid

6、intracranial mass lesions ：tumor, hematoma multiple sclerosis, neurosyphilis,11,Glucose in CSF,Normal value: Adult: 2.54.5mmol/L Child: 3.14.5mmol/L GCSF/GP：0.30.9,12,Clinical significance,Inflammation ： PM: TM: VM：normal Intracranial tumor, neurosyphilis Hypoglycemia,13,Chloride in CSF,Adult ：12013

7、0mmol/L TM：，102mmol/L PM：102116mmol/L。 Hypochloremia，such as severe vomit、diarrhea, dehydration,14,Normal Value,RBC：none WBC: adult：08106/L child：015106/L,Microscopic Examination,15,Clinical Significance,Infectious Diseases in CNS,16,行业特选,PURULENT MENINGITIS,1000-2000 106/L ，segmented neutrocyte,17,

8、Tuberculous Meningitis, 500 106/L，segment neutrocytes in early stage, and lymphocytes increase afterward, plasmocyte also observed,18,Viral Meningitis,1000106/L，lymphocytes,19,Clinical Significance,Brain tumor：lymphocytes and tumor cells Parasitic encephalopathy :eosinophile granulocyte Hemorrhage: RBC,20,21,General concepts,serous membrane fluid: pleural effussion peritoneum serous pericardial effusion,Serous Membr